2.A.1.14.51
Vacuoloar glutamate transporter 1, VGLUT1 of 483 aas and 12 TMSs in a 6 + 6 TMS arrangement.
Regulatory mechanisms of the six glutamate transporters (3 excitatory and 3 vesicular) in the response of the pacific oyster upon high-temperature stress have been studied (Zhang et al. 2024).
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| Accession Number: | K1PP83 |
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| Protein Name: | Vesicular glutamate transporter 1 |
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| Length: | 483 |
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| Molecular Weight: | 53106.00 |
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| Species: | Magallana gigas (Pacific oyster) [29159] |
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| Number of TMSs: | 9 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
L-glutamate(1-) |
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1: MYCLCQDAVK FRRRVYVVFL GFLGLLISIG FRSVFSMIMV HVVKSNQGEK EGLFGKCNVN
61: GTARDLSVTY SVPDTQFFQS AYFFGSFLMQ LPGGYLATRF SPRSSVLMIV LPFPIQYIQN
121: PAPVFIIRFL QGLVEGWSVP AMNGVISAWA PKSEKSRMVT FVYAGAYLSP ALAMVLTGVS
181: ACWVSWNASL FLYGGLGVIW SFAWVCTIYD TPTLHPGLHR SETDVFSKEG ANVSKGSQSV
241: AQRIPWSKIL RSLPVWAIIF GSFCRNWIFS MMITQVPQYF KDAFNKDIAT IGFTAALPEV
301: LMTIVTISGG VFIDKLIKHN LLSTSHGRKL AQCMGFGIEA LCLIGLRFVE TSEIALTLLS
361: VGVGFSGLAI SGYQVNPLDL APQYVSILTG LSRLGTLGAI LSTVVAGKLR QNNLQSWQNL
421: FTIAGSIHLA GVLFYGIFAS GERQPWAEPT ETRPLLAPVD SVPEFSRNVL EEDVGDSKFI
481: YIL