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2.A.1.15.3
2,4-Dichlorophenoxyacetate porter (Hawkins and Harwood 2002).

Accession Number:Q46M63
Protein Name:2,4-D transport protein
Length:460
Molecular Weight:47615.00
Species: [264198]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate 2,4-D, (2,4-dichlorophenoxy)acetate

Cross database links:

RefSeq: YP_025390.1    YP_293624.1   
Entrez Gene ID: 2847414    3607893   
Pfam: PF07690   
BioCyc: REUT264198:REUT_D6469-MONOMER   
KEGG: reu:Reut_D6469   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport

References (5)

[1] “Analysis, cloning, and high-level expression of 2,4-dichlorophenoxyacetate monooxygenase gene tfdA of Alcaligenes eutrophus JMP134.”  Streber W.R.et.al.   3036764
[2] “Nucleotide sequence of IS402 from Pseudomonas cepacia.”  Ferrante A.A.et.al.   1650732
[3] “Purification and characterization of maleylacetate reductase from Alcaligenes eutrophus JMP134(pJP4).”  Seibert V.et.al.   8226615
[4] “The tfdR gene product can successfully take over the role of the insertion element-inactivated TfdT protein as a transcriptional activator of the tfdCDEF gene cluster, which encodes chlorocatechol degradation in Ralstonia eutropha JMP134(pJP4).”  Leveau J.H.et.al.   8955303
[5] “Genetic organization of the catabolic plasmid pJP4 from Ralstonia eutropha JMP134 (pJP4) reveals mechanisms of adaptation to chloroaromatic pollutants and evolution of specialized chloroaromatic degradation pathways.”  Trefault N.et.al.   15186344

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNTTIDITDV IEKQSPNRTV GTLLVLSFLI MLCDGYDLQA IAFASPTIIA SWGIEKASFG 
61:	FIFSAGLLGV MLGGFLFGYL ADRIGRRPAL LLGTFIFSAF TLAAVLATNV TELAALRFFA 
121:	GLGIGGITPI CFALNVEYVP KRFHASVVGV VMIGYVIGIS VGGLFAAWLV PVFGWQVLFY 
181:	IGGLAPLVLL PILAIALPES IKYLVLAGRG GDTIARIVNA IDPSAQANAQ TRFVLEAEEA 
241:	RAKVGGWKES VKALFRGRLS RITPVLWLAF IANSVTVFFL ASWIPVLTVG TGRPATLAAI 
301:	GLTLFSAGGA FGGLFASRLI DRFGVGAMGA VPLVAAVFVV AVGSMAFSDT GFLSMLFIVG 
361:	FFVLGGHVGL MGSMGLFYAN ANRANGVGWA ISIGKLGSII GPAIAGILIA ANASIGTLFM 
421:	AAAAPLLIAG AGVVLLGRLQ KASDLAHATT AGHVADPLVS