2.A.1.19.13
The organic cation transporter, Oct1 (transports L-carnitine; expressed in vascular tissues of various organs and at sites of lateral root formation) (Lelandais-Briere et al, 2007). It also transports spermine and other polyamines and is induced by them (Sagor et al. 2016). It protects against the polyamine, cadaverine, which affects root length (Strohm et al. 2015).
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| Accession Number: | Q9CAT6 |
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| Protein Name: | Sugar transporter family protein aka Oct1 |
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| Length: | 539 |
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| Molecular Weight: | 59660.00 |
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| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
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| Number of TMSs: | 13 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
(R)-carnitine, carnitine |
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1: MEPSKQEVPK LMETPPNISN DSSATEKGEA TRQQQLPNNR YALTVDEVIE QHIGALGFAQ
61: ILHALLVSIA WIFDAQTTLI SIFSDAQPAA RLLATGAIVE GASLCGLASG EWEWIGPKSD
121: TVVSEWNLIC QHKFLVAVPS TLFFIGSLFG SGVYGYLADS WFGRKKTLLL SCVLTFVTAF
181: AISFSPNVWV YAFLRFANGF FRSGIGSCCI VLATEIVGKK WRGQVGQYGF FFFTLGFLSL
241: PLMAYLERKS WRNLYRIISF LPLGYAVCLL PFAYESPRWL LVKGRNKEAM VVLKKLARLN
301: GKQLPADLSL VDPIPERDDQ TSSSEKFWKT KWAVKRIIMV MMAGFGSGFV YYGIQLNAEN
361: LNFNLYLTVA VNALMEFPAV FIGSFLLGVM NRRPLFSNSS YLAGFACLLC AVLSIHRVIR
421: AISVAKWLQL AVEAVGFMAS STAYDVLYVY CVELFPTNVR NTAVSLLRQA FMLGASAAPL
481: LVALGRESAM MSFIVFGVAS VLSGIVSLWL RETRNAPLYE TLAQQGKAEE IENETIMIT