2.A.1.19.33 Solute carrier family 22 member 25 (Organic anion transporter UST6). Expressed exclusively in liver in both embryo and adult (Eraly et al. 2004). It may take up a nucleobase-containing compound (Meixner et al. 2020).
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Accession Number: | Q6T423 |
Protein Name: | Solute carrier family 22 member 25 |
Length: | 547 |
Molecular Weight: | 61008.00 |
Species: | Homo sapiens (Human) [9606] |
Number of TMSs: | 11 |
Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
Substrate |
organic anion |
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Entrez Gene ID: |
387601
|
Pfam: |
PF07690
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KEGG: |
hsa:387601
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[1] “Novel slc22 transporter homologs in fly, worm, and human clarify the phylogeny of organic anion and cation transporters.” Eraly S.A. et.al. 15054140
[2] “Human chromosome 11 DNA sequence and analysis including novel gene identification.” Taylor T.D. et.al. 16554811
[3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Team et.al. 15489334
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1: MAFQDLLDQV GGLGRFQILQ MVFLIMFNVI VYHQTQLENF AAFILDHRCW VHILDNDTIP
61: DNDPGTLSQD ALLRISIPFD SNLRPEKCRR FVHPQWKLIH LNGTFPNTSE PDTEPCVDGW
121: VYDQSSFPST IVTKWDLVCE SQPLNSVAKF LFMAGMMVGG NLYGHLSDRF GRKFVLRWSY
181: LQLAIVGTCA AFAPTILVYC SLRFLAGAAT FSIIVNTVLL IVEWITHQFC AMALTLTLCA
241: ASIGHITLGS LAFVIRDQCI LQLVMSAPCF VFFLFSRWLA ESARWLIINN KPEEGLKELR
301: KAAHRNGMKN AEDILTMEVL KSTMKQELEA AQKKHSLCEL LRIPNICKRI CFLSFVRFAS
361: TIPFWGLTLH LQHLGNNVFL LQTLFGAVTL LANCVAPWAL NHMSRRLSQM LLMFLLATCL
421: LAIIFVPQEM QTLRVVLATL GVGAASLGIT CSTAQENELI PSIIRGRATG ITGNFANIGG
481: ALASLMMILS IYSRPLPWII YGVFAILSGL VVLLLPETRN QPLLDSIQDV ENEGVNSLAA
541: PQRSSVL