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| Accession Number: | Q01818 |
| Protein Name: | VMT1 aka VMAT1 aka SLC18A1 aka CGAT |
| Length: | 521 |
| Molecular Weight: | 55935.00 |
| Species: | Rattus norvegicus (Rat) [10116] |
| Number of TMSs: | 12 |
| Location1 / Topology2 / Orientation3: | Cytoplasmic vesicle membrane1 / Multi-pass membrane protein2 |
| Substrate | hydron, monoamine molecular messenger, doxorubicin |
Cross database links:
| RefSeq: | NP_037284.2 |
|---|---|
| Entrez Gene ID: | 25693 |
| Pfam: | PF07690 |
| KEGG: | rno:25693 |
Gene Ontology
GO:0030659
C:cytoplasmic vesicle membrane
GO:0016021
C:integral to membrane
GO:0015238
F:drug transmembrane transporter activity
GO:0015893
P:drug transport
GO:0006836
P:neurotransmitter transport
GO:0055085
P:transmembrane transport
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References (1)[1] “A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter.” Liu Y.et.al. 1505023
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MLQVVLGAPQ RLLKEGRQSR KLVLVVVFVA LLLDNMLLTV VVPIVPTFLY ATEFKDSNSS 61: LHRGPSVSSQ QALTSPAFST IFSFFDNTTT TVEEHVPFRV TWTNGTIPPP VTEASSVPKN 121: NCLQGIEFLE EENVRIGILF ASKALMQLLV NPFVGPLTNR IGYHIPMFVG FMIMFLSTLM 181: FAFSGTYALL FVARTLQGIG SSFSSVAGLG MLASVYTDNY ERGRAMGIAL GGLALGLLVG 241: APFGSVMYEF VGKSSPFLIL AFLALLDGAL QLCILWPSKV SPESAMGTSL LTLLKDPYIL 301: VAAGSICLAN MGVAILEPTL PIWMMQTMCS PEWQLGLAFL PASVAYLIGT NLFGVLANKM 361: GRWLCSLVGM VAVGISLLCV PLAHNIFGLI GPNAGLGFAI GMVDSSLMPI MGYLVDLRHT 421: SVYGSVYAIA DVAFCVGFAI GPSTGGVIVQ VIGFPWLMVI IGTINIIYAP LCCFLQNPPA 481: KEEKRAILSQ ECPTETQMYT FQKPTKAFPL GENSDDPSSG E