2.A.1.2.110 Florfenicol-chloramphenicol resistance drug exporter, FloR of 404 aas and 12 TMSs (Braibant et al. 2005). This system in V. cholerae (98.8% identical) exports chlorampenicol (Saha et al. 2024).
|
Accession Number: | Q9S6C3 |
Protein Name: | Bcr/CflA family efflux transporter |
Length: | 404 |
Molecular Weight: | 42715.00 |
Species: | Salmonella enterica subsp. enterica serovar Typhimurium str. DT104 [85569] |
Number of TMSs: | 12 |
Location1 / Topology2 / Orientation3: |
Cell inner membrane1 / Multi-pass membrane protein2 |
Substrate |
chloramphenicol |
---|
1: MTTTRPAWAY TLPAALLLMA PFDILASLAM DIYLPVVPAM PGILNTTPAM IQLTLSLYMV
61: MLGVGQVIFG PLSDRIGRRP ILLAGATAFV IASLGAAWSS TAPAFVAFRL LQAVGASAML
121: VATFATVRDV YANRPEGVVI YGLFSSMLAF VPALGPIAGA LIGEFLGWQA IFITLAILAM
181: LALLNAGFRW HETRPLDQVK TRRSVLPIFA SPAFWVYTVG FSAGMGTFFV FFSTAPRVLI
241: GQAEYSEIGF SFAFATVALV MIVTTRFAKS FVARWGIAGC VARGMALLVC GAVLLGIGEL
301: YGSPSFLTFI LPMWVVAVGI VFTVSVTANG ALAEFDDIAG SAVAFYFCIQ SLIVSIVGTL
361: AVTLLNGDTA WPVICYATAM AVLVSLGLAL LRSRDAATEK SPVV