2.A.1.2.116
MDR efflux pump, Bcr/CflA, of 411 aas and 12 TMSs. Confer's chloramphenicol resistance (Yang et al. 2019).
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| Accession Number: | Q1D988 |
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| Protein Name: | Bcr/CflA family efflux transporter |
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| Length: | 411 |
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| Molecular Weight: | 43502.00 |
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| Species: | Myxococcus xanthus (strain DK 1622) [246197] |
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| Number of TMSs: | 12 |
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| Location1 / Topology2 / Orientation3: |
Cell inner membrane1 / Multi-pass membrane protein2 |
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| Substrate |
chloramphenicol, drug |
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1: MPDFKSPSWN HAVPAALLLM APFDLLASLA MDIYLPVVPA MPGILNTSPA IVQLTLSLYM
61: AVLGLGQMVF GPVSDRIGRR RVLLTGALLF AVTSFLLAGA SDAAMFVGLR LVQAMGASAA
121: LVATFATVRD VYAERPESAT LYSLFSAMLA FVPALGPIAG ALLMQRWGWR AIFITLGVLA
181: TAALLQALPR WHETRPAQGL QSRPAFRHIL RSATFWTYTL GFSAAMGSFF VFFSTAPRVL
241: IGQAGFSELG FSLAFATAAL AMILTTRFAK RFVGSWGLAG SLTRGMGMLL LGAGLLTAGQ
301: LLATPSFWTF VAPMWLIAAG IVFSVSVTAN GALQAFGDVA GTAVALYFCI QSLIVGVLGT
361: LMVVLLDGDT AWPLVGYASL MAGVTLTALQ RLQRRQRVLT KPAMAESPDA P