2.A.1.2.127 SLC18A2 or Vesicular monoamine transporter 2, VMAT2, of 562 aas with 13 TMSs in a 2 + 5 + 1 + 5 TMS arrangement. Mutations affect motility (Sveinsdóttir et al. 2022).
|
Accession Number: | Q5CZP4 |
Protein Name: | Slc18a2 protein |
Length: | 562 |
Molecular Weight: | 60855.00 |
Species: | Danio rerio (Zebrafish) [7955] |
Number of TMSs: | 13 |
Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
Substrate |
|
---|
1: GSNTSQATKK LRIQRAFHPG SDSKAQCKCA YKVISPSLSG SWIFIFKMGL FDALRDFSLL
61: TWLREERQSR RLILLIVFIA LLLDNMLLTV VVPIIPSYLY TVDDEAAQMV KNHSMTPLSP
121: SSTFQSIVSL YDNTTRVTGF SPQMSTAGPM SLAPTFVSPQ NQSDCPKADD QLLNENVKVG
181: LLFASKATVQ LITNPFIGPL TNRIGYQIPM FAGFCIMFVS TIMFAFSSSY TLLFLARSLQ
241: GVGSSCSSVA GMGMLASVYT DDEERGNAIG IALGGLAMGV LVGPPFGSVM YEFVGKTAPF
301: LILAVLAVLD GALQLFVLQP SKVEPESQKG TSLITLMKDP YILIAAGSIC FANMAIAMLE
361: PALPIWMMET MCPRKWQLGI AFVPASISYL IGTNIFAVLA HKMGRWLCSL IGMLLVGISI
421: LCVPLAKDIY GLIVPNFGVG FAIGMVDSSM MPIMGYLVDL RHVSVYGSVY AIADVAFCMG
481: FALGPSAGGA IARSIGFPWL MTIIGLVDIM FAPLCFFLRN PPANEEKMAI LMDSNCSMKT
541: RSYSTQGSSY QMGDDFDPES PE