| |
---|---|
Accession Number: | P69367 |
Protein Name: | Multidrug resistance protein mdtH aka YceL aka B1065 |
Length: | 402 |
Molecular Weight: | 44363.00 |
Species: | Escherichia coli [83333] |
Number of TMSs: | 12 |
Location1 / Topology2 / Orientation3: | Cell inner membrane1 / Multi-pass membrane protein2 |
Substrate | enoxacin, norfloxacin |
Cross database links:
RefSeq: | AP_001691.1 NP_415583.4 |
---|---|
Entrez Gene ID: | 946920 |
Pfam: | PF07690 |
BioCyc: | EcoCyc:B1065-MONOMER ECOL168927:B1065-MONOMER |
KEGG: | ecj:JW1052 eco:b1065 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0005215
F:transporter activity
GO:0046677
P:response to antibiotic
GO:0055085
P:transmembrane transport
| |
References (7)[1] “Cloning, overexpression, and characterization of glutaredoxin 2, an atypical glutaredoxin from Escherichia coli.” Vlamis-Gardikas A.et.al. 9111025 [2] “A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map.” Oshima T.et.al. 8905232 [3] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R.et.al. 9278503 |
External Searches:
|
Analyze:
Predict TMSs (Predict number of transmembrane segments) | ||||
FASTA formatted sequence |
|
1: MSRVSQARNL GKYFLLIDNM LVVLGFFVVF PLISIRFVDQ MGWAAVMVGI ALGLRQFIQQ 61: GLGIFGGAIA DRFGAKPMIV TGMLMRAAGF ATMGIAHEPW LLWFSCLLSG LGGTLFDPPR 121: SALVVKLIRP QQRGRFFSLL MMQDSAGAVI GALLGSWLLQ YDFRLVCATG AVLFVLCAAF 181: NAWLLPAWKL STVRTPVREG MTRVMRDKRF VTYVLTLAGY YMLAVQVMLM LPIMVNDVAG 241: APSAVKWMYA IEACLSLTLL YPIARWSEKH FRLEHRLMAG LLIMSLSMMP VGMVSGLQQL 301: FTLICLFYIG SIIAEPARET LSASLADARA RGSYMGFSRL GLAIGGAIGY IGGGWLFDLG 361: KSAHQPELPW MMLGIIGIFT FLALGWQFSQ KRAARRLLER DA