TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.1.2.39
Tetracycline-specific exporter, TetA41 (most like 2.A.1.2.4) (Thompson et al., 2007).

Accession Number:Q5JAK9
Protein Name:TetA (41)
Length:393
Molecular Weight:41140.00
Species:Serratia marcescens GN=tetA(41) PE=4 SV=1 [615]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Vacuole membrane1 / Multi-pass membrane protein2
Substrate tetracycline

Cross database links:

Pfam: PF07690   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015520 F:tetracycline:hydrogen antiporter activity
GO:0046677 P:response to antibiotic
GO:0015904 P:tetracycline transport
GO:0055085 P:transmembrane transport

References (1)

[1] “Novel tetracycline resistance determinant isolated from an environmental strain of Serratia marcescens.”  Thompson S.A.et.al.   17308196

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MKKPMLVILL TVLLDAVGIG LIMPILPALL RSLGGLDAGS VHYGALLAAY ALMQFLFSPI 
61:	LGALSDRFGR RPVLLISLAG AAADYLLMAF APTLAWLYLG RLLAGITGAN MAVATAYVTD 
121:	ITPVGQRARR FGLVGAVFGV GFIVGPLLGG SLGEWHLHAP FLAAAMMNAL NLVMAFFLLP 
181:	ESRKSRPRAA EKIRLNPFSS LRRLHGKPGL LPLAGIYLVM ALVSQAPATL WILYGQDRFG 
241:	WSMMVAGLSL AGYGACHALS QAFAIGPLVA RLGERKALLI GLAADAVGLA LLSVATRGWA 
301:	PFALLPFFAA GGMALPALQA LMAHKVDDDH QGELQGTLAS MGSLIGVAGP LVATALYAAT 
361:	RDVWPGLVWA LAAALYLVVP PLLARSRARD AAP