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2.A.1.2.42 The multidrug efflux pump, EmrD-3 (exports ethidium, linezolid, tetraphenylphosphonium chloride, rifampin, erythromycin, minocycline, trimethoprim, chloramphenicol, and rhodamine) (Smith et al., 2009).
Accession Number:	Q9KMQ3
Protein Name:	Multidrug resistance protein D
Length:	379
Molecular Weight:	40492.00
Species:	Vibrio cholerae [666]
Number of TMSs:	12
Location¹ / Topology² / Orientation³:	Cell membrane¹ / Multi-pass membrane protein²
Substrate	rhodamine 6G, rifampicin, trimethoprim, linezolid, chloramphenicol, minocycline, erythromycin A, ethidium

RefSeq:	NP_232665.1
Entrez Gene ID:	2612083
Pfam:	PF07690
KEGG:	vch:VCA0267
Gene Ontology GO:0055085 P:transmembrane transport
References (1) [1] “DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae.” Heidelberg J.F.et.al. 10952301

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MKTKPSLWLM VIMLMFPQIV ETIYSPVLGS IARSFSVSDA QAAQTLSVYF LAFALGVVIW 
61:	GVLADKWGRR PTMLVGLLIY GSATFIAMQT DSFTILMLAR VFSAFGIAVG SVVTQTILRD 
121:	VFSGHELRKV FSLMGIGISI SPVLGMLLGG QLAFAGGHQL VFLALFFIAL VLFVYNLCQL 
181:	PETQQVKPKI ALGCLVARMF KDRQVLLSAL LVALYNVALF SYYQLGAFIF SDLGLDAEQF 
241:	GYSGIALGLG SLIGSFLNKT LLAKQVPQRA LLLLAALLLI MGTIGVSLTL DSIGFVAAMI 
301:	LVVIAYGMAI PNILSTALVE YKSQAGSAGA LFGLLYYLLI GSGLALTGLV QRLGVVLLMC 
361:	AGITLLATLA RSSHIARLP

2.A.1.2.42
The multidrug efflux pump, EmrD-3 (exports ethidium, linezolid, tetraphenylphosphonium chloride, rifampin, erythromycin, minocycline, trimethoprim, chloramphenicol, and rhodamine) (Smith et al., 2009).

Cross database links:

Gene Ontology

References (1)

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Analyze:

2.A.1.2.42The multidrug efflux pump, EmrD-3 (exports ethidium, linezolid, tetraphenylphosphonium chloride, rifampin, erythromycin, minocycline, trimethoprim, chloramphenicol, and rhodamine) (Smith et al., 2009).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.1.2.42
The multidrug efflux pump, EmrD-3 (exports ethidium, linezolid, tetraphenylphosphonium chloride, rifampin, erythromycin, minocycline, trimethoprim, chloramphenicol, and rhodamine) (Smith et al., 2009).