2.A.1.2.55 Peptide exporter (Ala-Gln and Ala-branched chain amino and dipeptides) (Hayashi et al., 2010). May also export arabinose (but not xylose) and function as an MDR pump (Koita and Rao 2012).
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Accession Number: | P31126 |
Protein Name: | Uncharacterized MFS-type transporter ydeE |
Length: | 395 |
Molecular Weight: | 42659.00 |
Species: | Escherichia coli (strain K12) [83333] |
Number of TMSs: | 12 |
Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
Substrate |
peptide, dipeptide, arabinose, drug |
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Entrez Gene ID: |
946083
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Pfam: |
PF07690
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KEGG: |
ecj:JW1527
eco:b1534
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[1] “Genetic and functional analysis of the multiple antibiotic resistance (mar) locus in Escherichia coli.” Cohen S.P. et.al. 8383113
[2] “A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map.” Aiba H. et.al. 9097039
[3] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R. et.al. 9278503
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.” Hayashi K. et.al. 16738553
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1: MNLSLRRSTS ALLASSLLLT IGRGATLPFM TIYLSRQYSL SVDLIGYAMT IALTIGVVFS
61: LGFGILADKF DKKRYMLLAI TAFASGFIAI TLVNNVTLVV LFFALINCAY SVFATVLKAW
121: FADNLSSTSK TKIFSINYTM LNIGWTIGPP LGTLLVMQSI NLPFWLAAIC SAFPMLFIQI
181: WVKRSEKIIA TETGSVWSPK VLLQDKALLW FTCSGFLASF VSGAFASCIS QYVMVIADGD
241: FAEKVVAVVL PVNAAMVVTL QYSVGRRLNP ANIRALMTAG TLCFVIGLVG FIFSGNSLLL
301: WGMSAAVFTV GEIIYAPGEY MLIDHIAPPE MKASYFSAQS LGWLGAAINP LVSGVVLTSL
361: PPSSLFVILA LVIIAAWVLM LKGIRARPWG QPALC