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2.A.1.2.61
SPX domain-containing membrane protein At1g63010, called Vacuolar Phosphate Transporter 1 (VPT1), It transports phosphate > sulphate > nitrate > chloride and malate.  The vpt1 mutant plants were stunted and consistently retained less Pi than wild type plants, especially when grown in medium containing high levels of Pi. In seedlings, VPT1 was expressed primarily in younger tissues under normal conditions, but was strongly induced by high-Pi conditions in older tissues, suggesting that VPT1 functions in Pi storage in young tissues and in detoxification of high Pi in older tissues. As a result, disruption of VPT1 rendered plants hypersensitive to both low-Pi and high-Pi conditions, reducing the adaptability of plants to changing Pi availability (Liu et al. 2015).

Accession Number:Q2V4F9
Protein Name:SPX domain-containing membrane protein At1g63010
Length:697
Molecular Weight:78051.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Vacuole membrane1 / Multi-pass membrane protein2
Substrate

Cross database links:

Entrez Gene ID: 842604   
Pfam: PF07690    PF03105   
KEGG: ath:AT1G63010   

Gene Ontology

GO:0005794 C:Golgi apparatus
GO:0016021 C:integral to membrane
GO:0000325 C:plant-type vacuole
GO:0005774 C:vacuolar membrane
GO:0055085 P:transmembrane transport

References (3)

[1] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.”  Theologis A.et.al.   11130712
[2] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[3] “Mapping the Arabidopsis organelle proteome.”  Dunkley T.P.J.et.al.   16618929

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MVAFGKYLQR KQIEEWSGYY INYKLMKKKV KQYAEQIQGG SQHPRHVLKD FSRMLDTQIE 
61:	TTVLFMLEQQ GLLSGRLAKL RESHDAILEQ PDISRIFELR EAYRDVGRDL LQLLKFVELN 
121:	AIGLRKILKK FDKRFGYRFA DYYVKTRANH PYSQLQQVFK HVGVGAVVGA ISRNLHELQE 
181:	NEGSFYSIYD QPVLPAQDPV VEAINNAVDK LTFSTNFLNF LAQHALIMQD DLVTPSEDTI 
241:	DERSYHFNSL LLNLGNTFLY MVNTYIIVPT ADDYSMSLGA AATVCGVVIG SMAVAQVFSS 
301:	VYFSAWSNKS YFKPLVFSSI ALFIGNLMYA LAYDANSIAL LLLGRVCCGL GSARAVNRRY 
361:	ISDCVPLRIR MQASAGFVSA SALGMACGPA LAGLLQIKFK FYKFTFNQST LPGWVMAVAW 
421:	LFYLVWLCIS FREPLRDTED GEKNNRNETT SDRVESSRVE EGLRLPLLIT SGIKPEDEEE 
481:	CDESEESPED SHKPANSFIE AYRLLTPSVK VQLLIYFMLK YSMEILLSES SVITSYYFSW 
541:	TTSSVAIFLA CLGLTVLPIN ILVGSYISNM FEDRQILLTS EIIVFLGILF SFNLFVPYTV 
601:	PQYVISGLIM FVAAEVLEGV NLSLLSRVMS SRLSKGTYNG GLLSTEAGTL ARVVADATIT 
661:	LGGYLGRGHL LNATLLPSLV ICIGSIVATC CTYNSLY