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Accession Number: | P28246 |
Protein Name: | Bcr aka BICA aka BICR aka SUR aka SUXA aka B2182 |
Length: | 396 |
Molecular Weight: | 43353.00 |
Species: | Escherichia coli [83333] |
Number of TMSs: | 12 |
Location1 / Topology2 / Orientation3: | Cell inner membrane1 / Multi-pass membrane protein2 |
Substrate | L-cysteine, fosfomycin, tetracycline, bicozamycin, 3,6-diamino-10-methylacridinium chloride, sulfathiazole |
Cross database links:
RefSeq: | AP_002780.1 NP_416687.1 |
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Entrez Gene ID: | 944808 |
Pfam: | PF07690 |
BioCyc: | EcoCyc:BCR-MONOMER ECOL168927:B2182-MONOMER |
KEGG: | ecj:JW5363 eco:b2182 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0015238
F:drug transmembrane transporter activity
GO:0015893
P:drug transport
GO:0046677
P:response to antibiotic
GO:0055085
P:transmembrane transport
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References (5)[1] “Cloning and sequence analysis of an Escherichia coli gene conferring bicyclomycin resistance.” Bentley J.et.al. 8486276 |
External Searches:
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Analyze:
Predict TMSs (Predict number of transmembrane segments) | ||||
FASTA formatted sequence |
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1: MTTRQHSSFA IVFILGLLAM LMPLSIDMYL PALPVISAQF GVPAGSTQMT LSTYILGFAL 61: GQLIYGPMAD SFGRKPVVLG GTLVFAAAAV ACALANTIDQ LIVMRFFHGL AAAAASVVIN 121: ALMRDIYPKE EFSRMMSFVM LVTTIAPLMA PIVGGWVLVW LSWHYIFWIL ALAAILASAM 181: IFFLIKETLP PERRQPFHIR TTIGNFAALF RHKRVLSYML ASGFSFAGMF SFLSAGPFVY 241: IEINHVAPEN FGYYFALNIV FLFVMTIFNS RFVRRIGALN MFRSGLWIQF IMAAWMVISA 301: LLGLGFWSLV VGVAAFVGCV SMVSSNAMAV ILDEFPHMAG TASSLAGTFR FGIGAIVGAL 361: LSLATFNSAW PMIWSIAFCA TSSILFCLYA SRPKKR