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|---|---|
| Accession Number: | P33449 |
| Protein Name: | Multidrug resistance protein 1 |
| Length: | 389 |
| Molecular Weight: | 42232.00 |
| Species: | Bacillus subtilis (strain 168) [224308] |
| Number of TMSs: | 12 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | tetracycline, drug |
Cross database links:
| Entrez Gene ID: | 938680 |
|---|---|
| Pfam: | PF07690 |
| KEGG: | bsu:BSU24010 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0005215
F:transporter activity
GO:0046677
P:response to antibiotic
GO:0055085
P:transmembrane transport
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References (5)[1] “Efflux-mediated multidrug resistance in Bacillus subtilis: similarities and dissimilarities with the mammalian system.” Neyfakh A.A.et.al. 1675788 [2] “A protein that activates expression of a multidrug efflux transporter upon binding the transporter substrates.” Ahmed M.et.al. 7961792 [3] “Systematic sequencing of the 283 kb 210 degrees-232 degrees region of the Bacillus subtilis genome containing the skin element and many sporulation genes.” Mizuno M.et.al. 8969508 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MEKKNITLTI LLTNLFIAFL GIGLVIPVTP TIMNELHLSG TAVGYMVACF AITQLIVSPI 61: AGRWVDRFGR KIMIVIGLLF FSVSEFLFGI GKTVEMLFIS RMLGGISAAF IMPGVTAFIA 121: DITTIKTRPK ALGYMSAAIS TGFIIGPGIG GFLAEVHSRL PFFFAAAFAL LAAILSILTL 181: REPERNPENQ EIKGQKTGFK RIFAPMYFIA FLIILISSFG LASFESLFAL FVDHKFGFTA 241: SDIAIMITGG AIVGAITQVV LFDRFTRWFG EIHLIRYSLI LSTSLVFLLT TVHSYVAILL 301: VTVTVFVGFD LMRPAVTTYL SKIAGNEQGF AGGMNSMFTS IGNVFGPIIG GMLFDIDVNY 361: PFYFATVTLA IGIALTIAWK APAHLKAST