2.A.1.2.76
Major facilitator copper transporter 1, Mfc1. Takes up copper in meiotic sporulating cells; present in the forespore membrane. Induced under copper limitation. Required for normal forespore development and spore copper-dependent amine oxidase activity (Beaudoin et al. 2011).
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| Accession Number: | Q9HDX4 |
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| Protein Name: | Uncharacterized transporter B1A11.01 |
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| Length: | 495 |
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| Molecular Weight: | 55307.00 |
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| Species: | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [284812] |
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| Number of TMSs: | 12 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
copper(2+), copper(1+) |
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1: MSVSDKDFKD IELLPVKSIE SKDSIDQCDP LTWPIRIRII NTIIISFMTM LCMYGSSVFM
61: PSIPELCEKF GEPETLVVLG ATLYVIGVML GPLIFSPLSE LYGRRPLNIF GYTLFALMQI
121: PTALSVNLAM FVVFRFFSGF FGSVGLGIGA GSLSDMFSKR DRGKYIGIYF LGICLGPAIA
181: PIASGFIAGS SISWRWEFWI LLMLSGVSLL AGVVFLKETY APVLKRKQAK KLLEKQENQK
241: SVEVKISEIT ESSQQIDPDK SFAEVVHILV TTIRRPLHLL CTQPIMILIS LIVGTVYGIL
301: YLLFTAFAEV WISQYHFTSG LSGLTYISLS IGQVFAVFVL LPLNQKYWLS AVQKNNGVPE
361: PEFRLPMAFL GCFAIMTGMF IFGWTVQYKV FWFVPLIGTT LVGAGFVMTF NPMNMFIVDN
421: YGRYAASAMA AIAIPRNIFG ACFPLFAEKL FERLGYGWGS SLLAFLLVAI NFSIAALYMF
481: GKTIREKRPF DHTKY