2.A.1.2.77
CefT confers phenylacetate resistance (Fernández-Aguado et al. 2012). It has been reported to be a hydrophilic beta-lactam transporter that is involved in
the secretion of hydrophilic beta-lactams containing an α-aminoadipic
acid side chain (isopenicillin N, penicillin N and deacetylcephalosporin
C) (Cesareo et al. 2007; Ullán et al. 2002).
|
| Accession Number: | Q8NKG7 |
|---|
| Protein Name: | Multidrug resistant protein |
|---|
| Length: | 561 |
|---|
| Molecular Weight: | 61326.00 |
|---|
| Species: | Acremonium chrysogenum [5044] |
|---|
| Number of TMSs: | 12 |
|---|
| Substrate |
beta-lactam, phenylacetate |
|---|
1: MANNSGTTTV QLDDVLERSS TLNTLNNIDT VQHHEPRTSF ANNRQQAPAG GSSQSDATVG
61: PRHKLVTFAP DDPENPKNWS KAYKWYCTLV VSLTCFVVAF ASSVISADID GVMEEFNVSE
121: TAALVSISVF VVGFGVGPMV FAPLSEVYGR RIIYGSKLLF AVIFVIPCAV SKNLGTLLAC
181: RAIDGIAFSA PMTLVGGTLA DMWKNEERGV PMAAFSAAPF AGPAIGPLVG GYLSDAAGWR
241: WLYWIQLILS GIIWILITFT VPETYAPTIL AKRARKLRKS TGDPNHVTEQ ELDPRPISEQ
301: LRVFLTRPFQ LLFGELIVLL ISLYMSVLYG LLYMFFIAYP IVYKGGKGYS SGKTGLMFIP
361: VAVGVVLSAC CSPFVNTHYI SLAHFHGGKP PAEVRLIPMM LSCWLIPIGL FIFAWTSYPW
421: LSWAGPAMGG FPVGFGFIFL YNSANNYLVD SYQHQAASAL AAKTFIRSFW GAGVVLFTKQ
481: MYSRLGDQWA SSLIAFLALA CCAIPFLFWK YGARIRARSK YAYAGDETPA DVEKAKQRPA
541: EAGVLADADD LRRAISYVSN P