2.A.1.2.83 MmrA MFS protein. Homologous to drug exporter. RppA and MmrA are involved in amino acid uptake and efflux of antimicrobial agents including streptomycin, ethidium bromide and norfloxacin (Kimura et al. 2004).
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Accession Number: | Q1CZY0 |
Protein Name: | Major facilitator family protein MmrA |
Length: | 425 |
Molecular Weight: | 44692.00 |
Species: | Myxococcus xanthus (strain DK 1622) [246197] |
Number of TMSs: | 12 |
Substrate |
alpha-amino acid, norfloxacin, streptomycin, ethidium bromide |
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1: MPNQRQVSER AVVALIGAVQ FVNILDFVMV MPLGPDFAKE LGIASSHIGI IGGAYTAAAS
61: VAGLAGGYFL DRFDRRKALA VSMLGLVVAT AAGGFATGMS TLMLARVVAG IFGGPATSLS
121: LSIIADLVPV ERRGRALGAV MGAFSVASVA GVPMALKLAE FGGWRVPFFA VAAMGLLVVL
181: GAIFYLPPVR GHLDAGPRKQ AGVLELLANR DIQLSYVMTA LVMMAGFVLI PNLSAYLQQN
241: VGYPRDLLWL PYFIGGIASF ATLRVAGPMV DRYGSFKVGT VGSALVLLST YVGFVHLPRW
301: MPVPVIFTLF MVAMGTRNVA YNTLTSRVPD TPVRARFMSL QSAVQHMAAA VGAFLSARLL
361: TDLPDGTLGG IPRMAGVSMV LTLLLPALLW VVERRVHSRE QARALAVAPS QGMAVPLSPG
421: ADSHA