2.A.1.2.92
The CefM
protein of 482 aas and 12 TMSs. Probably involved in the translocation of penicillin N from the lumen of peroxisomes (or
peroxisome-like microbodies) to the cytosol, where it is converted into cephalosporin C (Teijeira et al. 2009). A null mutant
accumulates penicillin N, is unable to synthesize deacetoxy- and deacetyl-cephalosporin C as well as cephalosporin C, and shows impaired differentiation into arthrospores (Teijeira et al. 2009).
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| Accession Number: | B7FAY6 |
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| Protein Name: | CefM protein |
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| Length: | 482 |
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| Molecular Weight: | 52225.00 |
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| Species: | Acremonium chrysogenum [5044] |
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| Number of TMSs: | 12 |
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| Substrate |
penicillin N, penicillin N |
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1: MVKAEEDSAA LEAAIDNGRR HIVDFDGPTD PDNAVNWPAA RKWLNVFVLA AMTFIAALGS
61: SIAAPGVNQA IVDFDSTSSI LSSLIVSVYN VGLAIGPLIV APLSEMYGRL IPYHVTNVLF
121: VLFTIGCALS PNLPALVIFR MLAGMEASAV MTIGGATVAD LFIQEERGRA MAIWTFGPLM
181: GPAVGPAVGG YLAEAKGWRW VFWVVAIGGG FITGMFFLIA RETYPPVLLQ RKVNRLRQET
241: GNPLLTSALA DTSSRRARIS RSVRRPLVLL FRSPIVFLFS VFIAVVFSYQ FLLFVTIPSV
301: FGEIYDFSLG QIGLSYLGIA AGLLLGNAIF GQASDRILSK KSGGMELKPE FRLPLMIPGA
361: FCIPMCFFIY GWATYYKLHW MMPICATSLL GIGLNLSLMT IQVYLVDTYT LYSASALAAA
421: TILRSLFGAF LPLAGPPLYD ALGLGWGNST LGFIAVALIP VPFLFIRYGE AIRTNPRFQP
481: AL