2.A.1.21.4
Multidrug resistance efflux pump, Tap
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| Accession Number: | O32859 |
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| Protein Name: | Tap |
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| Length: | 409 |
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| Molecular Weight: | 42528.00 |
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| Species: | Mycobacterium fortuitum [1766] |
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| Number of TMSs: | 12 |
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| Location1 / Topology2 / Orientation3: |
Cell inner membrane1 / Multi-pass membrane protein2 |
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| Substrate |
drug |
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| Pfam: |
PF07690
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[1] “Molecular cloning and characterization of Tap, a putative multidrug efflux pump present in Mycobacterium fortuitum and Mycobacterium tuberculosis.” Ainsa J.A. et.al. 9811639
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1: MTNTKRGPLL LILFAALTAG AGNGITIVAF PWLVLQHNGS ALDASIVAMA GTLPLLVATL
61: IAGAAVDYLG RRRVSMISDL LSALSVAAVP VLALIFGVDA VNVAVLAVLA GLGAFFDPAG
121: MTARETMLPE AAGRAGWTLD HANSVYEAVF NLGYIVGPGI GGLMIATLGG INTMWVTAGA
181: FCCSILAISV LRLEGAGAPD RSVLTEAVLA GIVEGLRFVW YTPVLRTLAI VDLVATGLYM
241: PMESVLFPKY FTDRNEPTEL GWVLMALSIG GLLGALGYAV MSRYMSRRAT MLTAVITLGV
301: AMTVIAFLPP LPLILVLCAI VGFVYGPIAP IYNYVMQTTA PQHLRGRVVG VMGSLAYAAG
361: PLGLILAGPL ADAAGLHATF LALSLPMLLL GVVAVFLPRL RELDLASKP