2.A.1.21.8 The putative macrolide exporter, TIGR00900 (most similar to 2.A.1.21.1).
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Accession Number: | Q5WAS7 |
Protein Name: | Major facilitator (MFS) superfamily macrolide-efflux protein |
Length: | 415 |
Molecular Weight: | 46173.00 |
Species: | Bacillus clausii (strain KSM-K16) [66692] |
Number of TMSs: | 12 |
Location1 / Topology2 / Orientation3: |
Endoplasmic reticulum-Golgi intermediate compartment membrane1 / Single-pass type I membrane protein2 |
Substrate |
macrolide |
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1: MSKKSEIIRI LKENRNYRHL LLTTTISGLA TWGAFIAMLM LLSEITETGV QLGALWALSG
61: IVPLFMSFGL GGIIDRFHTR TVLIVSEWVR APLHALFILV PFFDGWLAWT LFFIVRFVIG
121: VFNSLNAVAR QTIIPEIIKG DDLIVANSLN FTLTSTIRLI GAATGGTVIT LIDPNYFWVL
181: ASIAFVISAV LVSRLQVKRE KVKPKERHFI KELKVGLTIA KNKVFIRYVL LFALTGGLII
241: GSFNLMLQQM AVITYDMPAI GLSLLYIAEG ATSVALGIWI ANRKFMFVKI HTYGWIYILM
301: GATWALFGFT QTIHQGMFVI FLFAAVGGFV VPFERMVMQT HVEANARGRI FGLWNTCSLL
361: SINIGALITG MVIDYVGLAY VPLIVAIFEI ILGIVFFVQF KGRTTDEAKK FGEVG