2.A.1.25.3 The AmpG peptidoglycan degradation product uptake porter is part of the peptidoglycan recycling pathway (Garcia and Dillard, 2008). It also plays a role in peptidoglycan remodeling, recycling, and toxic fragment release as well as pathogenesis (Schaub and Dillard 2019).
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Accession Number: | Q5F6G0 |
Protein Name: | AmpG |
Length: | 427 |
Molecular Weight: | 46381.00 |
Species: | Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090) [242231] |
Number of TMSs: | 12 |
Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
Substrate |
peptidoglycan |
---|
1: MTASKSGFIG QIFSRNMLVC IFTGFASGLP LYFLINLIPA WLRSEQVDLK SIGLMALIGL
61: PFTWKFLWSP LMDAVRLPVL GRRRGWMLLT QAGLLAALAA YAFLNPRNHL PLIAGLSVLV
121: AFFSASQDIV LDAFRREILS DEELGLGNSV HVNAYRVAAL IPGSLSLVLA DRMPWSEVFV
181: ITSLFMLPGL LMTLFLAHEP VLPPSVPKTL KQTVVEPFKE FFMRKGIASA VCVLLFIFLY
241: KLGDSMATAL ATPFYLDMGF SKTDIGLIAK NAGLWPAVAA GILGGVWMLK IGVNKALWLF
301: GAVQAITVLG FVWLAGFGHF DTVGTGERLM LAAVIGAEAV GVGLGTAAFV SYMARETNPA
361: FTATQLALFT SLSAVPRTVI NSFAGYLIEW MGYVPFFRLC FILALPGMLL LLKVAPWNGE
421: KTQDAGR