2.A.1.26.3 Multidrug resistance efflux porter, BC3310 of 396 aas and 12 TMSs. Exports ethidium bromide, sodium dodecyl sulfate and silver nitrate. D105 in TMS4 is essential for activity (Kroeger et al. 2015).
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Accession Number: | Q81B77 |
Protein Name: | Transporter, MFS superfamily |
Length: | 396 |
Molecular Weight: | 43576.00 |
Species: | Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711) [226900] |
Number of TMSs: | 12 |
Substrate |
ethidium bromide, sodium dodecyl sulfate, silver(1+) nitrate |
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1: MRFTFWIMVG IVAISGLSQG MLLPAIAMIF EQEGVSSSIN GIHATALYIG ILVISPFLEK
61: PMQRFGMKPI IVIGGFLVII SLFFFTQTFS FWVWFILRFL VGVGDHMLHV GTQTWITTTS
121: DPSKIGRQVS IYGVFFGIGF AVGPYLASTV QYGLATPFII STILCLIGWL LLLPTKNAFP
181: AQDEREVKSE SSFSRYKQVV GLGWIALLGP LAYGVLEAML NSNLPVYALR KGWSVSDVSF
241: LLPAFAVGGI ITQIPLGILS DKYGRDRILT WTFSISTGIF LLAAVFDQYY WIVFACMLLA
301: GMVIGSCFSL GLGFMTDLLP RHLLPAGNIL SGIAFSLGSI MGPVLGGVFI EKIQYTSFFI
361: AVMIIMGILA MLYMVYMKNQ FASRKIESRL GHDKTT