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2.A.1.3.28 MDR multidrug efflux pump, EbrE (involved in colony growth, dependent on Ca²⁺, Mg²⁺, Na⁺ and K⁺) (Lee et al., 2007)
Accession Number:	Q939A4
Protein Name:	EbrE
Length:	521
Molecular Weight:	53747.00
Species:	Streptomyces lividans [1916]
Number of TMSs:	12
Location¹ / Topology² / Orientation³:	Cell inner membrane¹ / Multi-pass membrane protein²
Substrate	drug

Pfam:	PF07690
Gene Ontology GO:0055085 P:transmembrane transport
References (1) [1] “Repressed multidrug resistance genes in Streptomyces lividans.” Lee L.F.et.al. 12937892

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MRTVAAMTTN PPRAGRREWT ALAVLMLPLL LVSMDVSVLF FAIPEISADL EPSGTQQLWI 
61:	FDIYGFVLAG LLMTMGSLGD RIGRRRLLLV GAAAFGAASL LAAYAHTAET LIAARAVLGI 
121:	GGATLMPSTM ALVRTMFTDP AQRAKAIGLW SGVMTAGIAL GSVMSGVLVE HFWWGSVFLV 
181:	NLPAMALLLI LGPMLLPESK NPSPGRFDLL SVPLSMAAVL PVVYGLKELP SEGWNVRYVV 
241:	SITVGLLFAA LFVHRQRTAA SPMISPALFR GHGFTPAVVL NLVSAFGMMG SSYFTTQYLQ 
301:	SVLDKSALEA ALWALLPSVF IGFAAPLAMR LVQLGVERAY VVAGGFVVAA CGYALLACAG 
361:	TDSLWLVLAA CGVMAGGIVA VMSQLTDLAL SSAPVEKAGA ASSLMETGTE FGGALSMAVL 
421:	GSVGTAVYHH EMPASAPDAA RETLGGALSV AARLPGSAGE ALATAAREAF TDGMRGASIA 
481:	GAVLLLAAAL PAARALRGIR VRENAATENA GQADSLSPSG V

2.A.1.3.28
MDR multidrug efflux pump, EbrE (involved in colony growth, dependent on Ca²⁺, Mg²⁺, Na⁺ and K⁺) (Lee et al., 2007)

Cross database links:

Gene Ontology

References (1)

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2.A.1.3.28MDR multidrug efflux pump, EbrE (involved in colony growth, dependent on Ca2+, Mg2+, Na+ and K+) (Lee et al., 2007)

Cross database links:

Gene Ontology

References (1)

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Analyze:

2.A.1.3.28
MDR multidrug efflux pump, EbrE (involved in colony growth, dependent on Ca²⁺, Mg²⁺, Na⁺ and K⁺) (Lee et al., 2007)