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2.A.1.3.39 The antimicrobial efflux pump, LmrS. Exports linezolid and tetraphenylphosphonium chloride (TPCL) > sodium dodecyl sulfate (SDS), trimethoprim, and chloramphenicol. (most similar to LmrB (2.A.1.3.30)) (Floyd et al., 2010).
Accession Number:	Q5HE38
Protein Name:	Drug resistance transporter, EmrB/QacA subfamily
Length:	480
Molecular Weight:	52638.00
Species:	Staphylococcus aureus (strain COL) [93062]
Number of TMSs:	14
Substrate	trimethoprim, linezolid, chloramphenicol, sodium dodecyl sulfate

Entrez Gene ID:	3237419
Pfam:	PF07690
KEGG:	sac:SACOL2157
Gene Ontology GO:0016021 C:integral to membrane GO:0005886 C:plasma membrane GO:0055085 P:transmembrane transport
References (1) [1] “Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain.” Gill S.R.et.al. 15774886

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MAKVELTTRR RNFIVAVMLI SAFVAILNQT LLNTALPSIM RELNINESTS QWLVTGFMLV 
61:	NGVMIPLTAY LMDRIKTRPL YLAAMGTFLL GSIVAALAPN FGVLMLARVI QAMGAGVLMP 
121:	LMQFTLFTLF SKEHRGFAMG LAGLVIQFAP AIGPTVTGLI IDQASWRVPF IIIVGIAILA 
181:	FVFGLVSISS YNEVKYTKLD KRSVMYSTIG FGLMLYAFSS AGDLGFTSPI VIGALILSMV 
241:	IIYLFIRRQF NITNALLNLR VFKNRTFALC TISSMIIMMS MVGPALLIPL YVQNSLSLSA 
301:	LLSGLVIMPG AIINGIMSVF TGKFYDKYGP RPLIYTGFTI LTITTIMLCF LHTDTSYTYL 
361:	IVVYAIRMFS VSLLMMPINT TGINSLRNEE ISHGTAIMNF GRVMAGSLGT ALMVTLMSFG 
421:	AKIFLSTSPS HLTATEIKQQ SIAIGVDISF AFVAVLVMAA YVIALFIREP KEIESNRRKF

2.A.1.3.39
The antimicrobial efflux pump, LmrS. Exports linezolid and tetraphenylphosphonium chloride (TPCL) > sodium dodecyl sulfate (SDS), trimethoprim, and chloramphenicol. (most similar to LmrB (2.A.1.3.30)) (Floyd et al., 2010).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.1.3.39The antimicrobial efflux pump, LmrS. Exports linezolid and tetraphenylphosphonium chloride (TPCL) > sodium dodecyl sulfate (SDS), trimethoprim, and chloramphenicol. (most similar to LmrB (2.A.1.3.30)) (Floyd et al., 2010).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.1.3.39
The antimicrobial efflux pump, LmrS. Exports linezolid and tetraphenylphosphonium chloride (TPCL) > sodium dodecyl sulfate (SDS), trimethoprim, and chloramphenicol. (most similar to LmrB (2.A.1.3.30)) (Floyd et al., 2010).