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2.A.1.3.40
The phenazine resistance pump. It also exports D-alanyl-griseoluteic acid; possibly in conjunction with a chaperone protein, EhpR. The crystal structure of EhpR is known (Yu et al., 2011). Note: Phenazines are toxic redox active secondary metabolites that many bacteria secrete. It may be  involved in the export of griseoluteic acid, an intermediate in the biosynthesis of the broad-spectrum phenazine antibiotic, D-alanylgriseoluteic acid (Dagher et al. 2021).

Accession Number:O32600
Protein Name:EhpJ
Length:478
Molecular Weight:50797.00
Species:Enterobacter agglomerans (Erwinia herbicola) [549]
Number of TMSs:14
Substrate phenazine

Cross database links:

Pfam: PF07690   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0055085 P:transmembrane transport

References (2)

[1] “Antibiotic production by Erwinia herbicola Eh1087: its role in inhibition of Erwinia amylovora and partial characterization of antibiotic biosynthesis genes.”  Kearns L.P.et.al.   9572960
[2] “Characterization of a novel phenazine antibiotic gene cluster in Erwinia herbicola Eh1087.”  Giddens S.R.et.al.   12139622

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MLRNKMAFFG LCLGFFIIMM DTTTVPLIYT SIINEYQVTP AMAAWVNNSY LITYAGFLLF 
61:	GGRLGDAINR KTVLYYALII LAIGALLSGS GQTLIQVILG RALMGVGAGL LTPQSMAFIS 
121:	IIFTQGGRGT ALGIWGAVAG IATATGPVVT QIFLQTIGWR WIIFIYIPVA LIALIFAVIC 
181:	LPGTPGNGAK SKELLSNAIA GIALAAIILG LELLNGGMQG MTTGLLLLLS GILLFAFMLH 
241:	GELKNHKQYL LPSSLWKDRA FLRTCLISGL LGFGLTAFYL PLAYLIELRM GFGPVAISVI 
301:	MVTIALANAL VGPFAGHFSD KAAPETLIRW GMCCFAAATM IIGITGLMTY GGSVAFIIII 
361:	TAMALAGIGT GLAFAPLANQ AFSRATFNNF GRAAAFFNVV RQMMSALGSV AIAIFFDYLL 
421:	HNSEKRSFTN ENSLFSSGSP SVAFASFGCF LIITGLLGLG AWLSRTYPVV QSVIKETK