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2.A.1.3.43 MFS efflux pump, AmvA (AedF). Mediates drug, dye, detergent, antibiotic and disinfectant resistance (Rajamohan et al., 2010; Hassan et al. 2011). 98.6% identical to AdeF (2.A.1.3.46).
Accession Number:	C4PAW9
Protein Name:	Major facilitator superfamily efflux pump
Length:	492
Molecular Weight:	52805.00
Species:	Acinetobacter baumannii [470]
Number of TMSs:	14
Substrate	disinfectant, drug, dye, detergent

Pfam:	PF07690
Gene Ontology GO:0016021 C:integral to membrane GO:0055085 P:transmembrane transport
References (1) [1] “Molecular and functional characterization of a novel efflux pump, AmvA, mediating antimicrobial and disinfectant resistance in Acinetobacter baumannii.” Rajamohan G.et.al. 20573661

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MQKKWLILTI IVLIYLPVTI DATVMHVATP SLSAALNLTA NQLLWIIDIY SLIMAGLILP 
61:	MGALGDRIGF KKLLFIGTAV FGVGSLAAAF SPTAYALIAS RAILGLGAAM LIPATLSGIR 
121:	NAFTEEKQRN FALGIWSTVG GGGAAFGPLV GGFVLEHFHW GAVFLINIPI ILAVLVMIVM 
181:	IIPKQQEKTD QPINLGQALV LVVAILSLIY SIKSAMYNFS VLTVVMFVVG ISTLIHFIRS 
241:	QKRATTPMID LELFKHPVIS TSIVMAVVSM IALVGFELLL SQELQFVHGF SPLQAAMFII 
301:	PFMIAISLGG PLAGICLNKW GLRRVSSLGI LVSALSLWGL AQLNFSTDHF LAWTCMVFLG 
361:	FSIEIALLAS TAAIMSSVPP QKASAAGAIE GMAYELGAGL GVAIFGLMLS WFYSRSIILP 
421:	AELPSNLIEK ASISIGETMQ LASNLENPLG GQLIVVAQQA FSYAHSWVLT LSAICFFLLT 
481:	VFVWFSFPKK VN

2.A.1.3.43
MFS efflux pump, AmvA (AedF). Mediates drug, dye, detergent, antibiotic and disinfectant resistance (Rajamohan et al., 2010; Hassan et al. 2011). 98.6% identical to AdeF (2.A.1.3.46).

Cross database links:

Gene Ontology

References (1)

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2.A.1.3.43 MFS efflux pump, AmvA (AedF). Mediates drug, dye, detergent, antibiotic and disinfectant resistance (Rajamohan et al., 2010; Hassan et al. 2011). 98.6% identical to AdeF (2.A.1.3.46).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.1.3.43
MFS efflux pump, AmvA (AedF). Mediates drug, dye, detergent, antibiotic and disinfectant resistance (Rajamohan et al., 2010; Hassan et al. 2011). 98.6% identical to AdeF (2.A.1.3.46).