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| Accession Number: | Q54806 |
| Protein Name: | Ptr |
| Length: | 501 |
| Molecular Weight: | 50903.00 |
| Species: | Streptomyces pristinaespiralis [38300] |
| Number of TMSs: | 14 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | hydron, pristinamycin IA, rifamycin SV, pristinamycin IIA |
Cross database links:
| Pfam: | PF07690 |
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Gene Ontology
GO:0016021
C:integral to membrane
GO:0015520
F:tetracycline:hydrogen antiporter activity
GO:0046677
P:response to antibiotic
GO:0015904
P:tetracycline transport
GO:0055085
P:transmembrane transport
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References (1)[1] “Molecular characterization and transcriptional analysis of a multidrug resistance gene cloned from the pristinamycin-producing organism, Streptomyces pristinaespiralis.” Blanc V.et.al. 8596448
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MTATTTETSK APSGGHPQRW LILGVICLAQ LTVLLDNTVL SVAIPSLTRE LHASTADIQW 61: MINAYSLVQS GLLLTAGNAA DRYGRRKMLV AGLALFGIGS LAAGLAQTSG QLIAARAGMG 121: VGGALLMTTT LAVVVQVFDE TERVKAIALW STVSSLGFAA GPLIGGVMLE HYWWGAIFLI 181: NIPVAVIGLV AVVLLVPESK NPQGDRPDLL GAVLSTIGMT AVVYAIISGP DHGWTSTQVL 241: ASAALGALFL GAFVFWELRI PYPMLDMHFF RNQRFIGAVA GAILVAFGMT GSLFLLTQHL 301: QFVLGYGALD AGLRTAPLAL TVVALNLTGM GARLLRIFGT PVTIAVGMAL VSGGLAAIAV 361: LGAGGYNGML LGLVVMGAGV ALSMPAMANA IMSAIPPEKA GVGAGINGTL AEFGNGLGVA 421: VLGAVLNSRF AALVPAAVGA TSLPAALAAA DDAGERARIS DAFASGLETS QLVGAVAVLA 481: GGLLAALLLR RAERADPPAK A