2.A.1.3.52 Drug resistance protein YOR378W. Does not export boron (Bozdag et al. 2011).
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Accession Number: | Q08902 |
Protein Name: | Drug resistance protein YOR378W |
Length: | 515 |
Molecular Weight: | 56110.00 |
Species: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292] |
Number of TMSs: | 14 |
Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
Substrate |
drug |
---|
DIP: |
DIP-4051N
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Entrez Gene ID: |
854560
|
Pfam: |
PF07690
|
KEGG: |
sce:YOR378W
|
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[1] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.” Dujon B. et.al. 9169874
[2] “Gene transcription analysis of Saccharomyces cerevisiae exposed to neocarzinostatin protein-chromophore complex reveals evidence of DNA damage, a potential mechanism of resistance, and consequences of prolonged exposure.” Schaus S.E. et.al. 11562456
[3] “New weakly expressed cell cycle-regulated genes in yeast.” de Lichtenberg U. et.al. 16278933
[4] “A global topology map of the Saccharomyces cerevisiae membrane proteome.” Kim H. et.al. 16847258
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1: MSTSSSVTQK NLDTNAEALK KEDKVLSEFD IQDERPKSLL WESAFVGVLC SAQLMTQAGL
61: GQSLAPLHII GNSFGTTNAG QLSWFASAYS LTVGTFILIA GRLGDIFGHK KFFVLGFFWY
121: ALWSLLAGFS VYSNQIFFDC CRAFQGMGPA FLLPNAIAIL GRTYKPGRRK NMVFSLFGAS
181: APGGFFLGAV FSSMLGQLAW WPWAYWIMGI ACFVLAVAGY FVIPHTPMPS RDASSFKLLE
241: RIDFAGSVTG VVGLILFNFA WNQGPVVGWQ TPYTYALLIV GTFFLVIFAY IESRAAFPLL
301: PFAALSSDTA FVLSCIAAGW ASFGIWIFYT WQFMEDSRGQ TPLLSSAQFS PVAISGFCAA
361: VTTGFLLSHT PPSTVMLFAM TAFTVGTILI ATAPVHQTYW AQTFVSIIVM PWGMDMSFPA
421: ATIMLSDSMP HEHQGLAASL VNTVVNYSIS IGLGIAGTIE SRVNDGGAKP LKGYRCSWYM
481: GIGLSGLGIF VAATYAWSTF MKSKKRISEK QHFIE