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|---|---|
| Accession Number: | P50080 |
| Protein Name: | Azole resistance protein 1 |
| Length: | 613 |
| Molecular Weight: | 67169.00 |
| Species: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292] |
| Number of TMSs: | 14 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | azole, 1H-pyrrole |
Cross database links:
| DIP: | DIP-7543N |
|---|---|
| Entrez Gene ID: | 853139 |
| Pfam: | PF07690 |
| KEGG: | sce:YGR224W |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0045118
F:azole transporter activity
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References (5)[1] “Sequence analysis of the 43 kb CRM1-YLM9-PET54-DIE2-SMI1-PHO81-YHB4-PFK1 region from the right arm of Saccharomyces cerevisiae chromosome VII.” van der Aart Q.J.M.et.al. 8701610 [2] “The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.” Tettelin H.et.al. 9169869 [3] “Expression of the AZR1 gene (ORF YGR224w), encoding a plasma membrane transporter of the major facilitator superfamily, is required for adaptation to acetic acid and resistance to azoles in Saccharomyces cerevisiae.” Tenreiro S.et.al. 11113970 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MKGEPKTYSM SDLSYYGEKA QQQNEKQQKQ YVVRRNSTQS TSKQNVSVVL EDNASESNEL 61: PKGFILYASL IALALSLFLA ALDIMIVSTI IEEVAKQFGS YSEIGWLFTG YSLPNALLAL 121: IWGRIATPIG FKETMLFAIV IFEIGSLISA LANSMSMLIG GRVIAGVGGC GIQSLSFVIG 181: STLVEESQRG ILIAVLSCSF AIASVVGPFL GGVFTSSVTW RWCFYVNLPI GGLAFFLFLF 241: FYNPGLSTFQ ETMDNIRKFP SQFIEIVRNV AYHLLKIKGF SKLNGWRKPF MELIFMYDII 301: EFVFCSAGFT CILLAFTFGG NRYAWNSASI IILFIIGIVL VVLAGIYDFL VFPKFNIVKA 361: TPHYQPLMSW TNIKKPGIFT VNIALFLTCA GYISQFTYIV QYFQLIYNDS AWRAAVHLVA 421: CIISTVVTAI LCGAITDKTR QIKPIIVISS IFGVVGAGIL TLLNNNANNS AHIGLLILPG 481: VAFGGLAQSS MLASQIQLDK KSPTFRSDFV SITTFNTFCK NLGQALGGVI SNTVFSAAAI 541: KKLTKANIQL PDGTTVDNLV IYRQTNFDGS HSKLGNIISE SLTDVFYMAL GFYALSLIFA 601: VFASNKKVTA SLR