2.A.1.3.62 MDR efflux pump, AedC (Hassan et al. 2011). Shown to export chloramphenicol and tetracycline.
|
Accession Number: | A3M347 |
Protein Name: | Putative MFS family drug transporter |
Length: | 507 |
Molecular Weight: | 54839.00 |
Species: | Acinetobacter baumannii (strain ATCC 17978 / NCDC KC 755) [400667] |
Number of TMSs: | 15 |
Substrate |
chloramphenicol, tetracycline |
---|
1: MKTQTPFAEL SGGRLLLAAF VIALSNFMVV LDTTIANVSV PHITGNLAVS STQGTWVVTS
61: YAVAEAICVP LTGWLAGRFG TVRVFIFGLI GFTVFSFLCG LATSLEMLVF FRIGQGLCGG
121: PLMPLSQTLL MRIFPQEKHA QAMGLWAMTT VVGPILGPIL GGLISDNLSW HWIFFINLPV
181: GIVCVLAAMR LLRVAETETI SLRIDTVGLG LLILWIGALQ LMLDLGHERD WFNSTSIVIL
241: ALTAAIGFVV FLIWELTDKH PVVDVKVFRH RGFAISVLAL SLGFGAFFGS IVLIPQWLQM
301: NLSYTATWAG YLTATMGFGS LTMSPIVAKL STKHDPRALA SFGLILLGIV TLMRAFWTTD
361: ADFMALAWPQ ILQGFAVPFF FIPLSNIALG SVLQQEIASA AGLMNFLRTM AGAIGASIAV
421: TVWDDHAKVA RSEMVSNLHT TEVQNTLLQN GFTADSTLGI ISNLVDKEAI TMSANHVFLL
481: FAIVFVFAGL VIWLCPKPKQ VSGMPSH