2.A.1.3.65
ThMFS1 of 563 aas and 14 TMSs. Catalyzes export of fungicides causing tolerance. It exports trichodermin, but it is not the only exporter of this secondary metabolite (Liu et al. 2012). Trichothecenes are the sesquiterpenes secreted by Trichoderma spp. residing in the rhizosphere.
These compounds have been reported to act as plant growth promoters and bio-control agents (Chaudhary et al. 2016).
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| Accession Number: | H2E274 |
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| Protein Name: | MFS multidrug transporter |
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| Length: | 563 |
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| Molecular Weight: | 60755.00 |
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| Species: | Trichoderma harzianum [5544] |
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| Number of TMSs: | 14 |
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| Substrate |
trichodermin |
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1: MADTDTDNNA STVSSRDQSS SDLFEVLGPE ETSNITTGDA EKVTNEDEET KEDGTAYPTG
61: FQLGLIILAL CLSVFLIALD NAIIATAIPK ISDEFHSLPD VGWYGSAYLL TTAALQLLFG
121: KFYVFFRLKW VYLIAICLFE LGSLICGVAQ NSVTLIIGRA VAGLGAAGIM SGALLILAHS
181: VPLVKRPMYA GMIGSMYGIA SVAGPLLGGV FTDKATWRWC FFINLPVGAI TVVVILFFFP
241: EPKQDKAVNE QATFAEKVMR FDPIGNLLFI PAIICLLLAL QWGGTLYSWN NDRIIALFVL
301: FGVLIIGFIF VQRRQGENAT VPPRIISNRS VWASCLYIFF LGSSFYLMVY YVPIWFQSVQ
361: GASAIESGTR NLPVLISVVV LTIFSGGLVT ALGYYAPFMI LGTIVMSIGS GLLSTFQPDT
421: RSPAWIGYQI LFGAGVGMGM QQPLMAIQNV LDIRDIPTGT SMVTFLQTLG GALFVSVAQS
481: VFTNQLLRSL ATYVPDLDPD TVFSTGVTNL QKALPKEDLP GIELAYNEAV TRAFLVATAL
541: SATSILGSAT IPWKSVKAKA KNP