2.A.1.3.81 multidrug (tetracycline, kanamycin, rhodamin 6G, ampicillin, acriflavine, ethidium bromide, and tetraphenylphosphonium chloride) resistance exporter, MdeA, of 453 aas and 14 TMSs (Kim et al. 2013).
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Accession Number: | WP_024786390.1 |
Protein Name: | WP_024786390.1 multidrug efflux MFS transporter MdeA [Streptococcus mutans] |
Length: | 454 |
Molecular Weight: | |
Species: | Streptococcus mutans [1309] |
Number of TMSs: | 14 |
Substrate |
rhodamine 6G, ampicillin, tetracycline, 3,6-diamino-10-methylacridinium chloride, ethidium bromide, kanamycin |
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1: MTKRLQDFFI TVIAGMGMLL STLDTGIINV ALSFLRGQFQ TTTNIASFTI TGYTLALAIS
61: ILPLGVLSDK FGKLKISYLG FVLFGLSSLF CGFANSIGWL ITGRIIQGMG AAALQATSAA
121: LITTLVSEDR KNSAISILGV MIGLGPVLGP SLGGVLLSLN LWRFIFWINV PFALIVIICN
181: HYLLTKVSEQ TSEWTLDSLG TVLNASMLVC LLLGLSLLSK PHLLGISLIL IIISFLIGIW
241: FYRLECSKES ALVNVKGLSE NPRVLSYLFQ TVAFGFASAM IFLLPPFIFE QLYHLGVGQT
301: GFLLLGAPAG LVLFSRISGK INDGSKNKSF SHIGLGIIIL SLIFLLLLTP SWPYLFLTLG
361: LFIYGIGGGY FQPANMASIM LASPMKMQGS TGALQRMVQN IAISAGSAIG STCLNLWSNN
421: LLLATRIGWG ITLVLVIFSL KELTPFKMTN KTE