2.A.1.33.1
MFS homologue, YqgE. It is cotranscribed with ftsI, encoding the peptidoglycan transpeptidase that crosslinks peptidoglycan strands, releasing free D-alanine. Possibly YqgE is a D-alanine uptake porter. Its expression causes a decrease in the amount of sigma W synthesis, the sigma factor for genes involved in detoxification and antimicrobial synthesis (Turner and Helmann 2000).
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| Accession Number: | P54487 |
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| Protein Name: | YqgE |
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| Length: | 430 |
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| Molecular Weight: | 48260.00 |
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| Species: | Bacillus subtilis [1423] |
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| Number of TMSs: | 12 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
D-alanine |
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| RefSeq: |
NP_390380.2
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| Entrez Gene ID: |
938196
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| Pfam: |
PF07690
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| KEGG: |
bsu:BSU25010
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[1] “Systematic sequencing of the 283 kb 210 degrees-232 degrees region of the Bacillus subtilis genome containing the skin element and many sporulation genes.” Mizuno M. et.al. 8969508
[2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.” Kunst F. et.al. 9384377
[3] “From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later.” Barbe V. et.al. 19383706
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1: MSKLKKVIGD VDVNKGLLFL LTIGGLYSLG IALSNTFVNV YLWKQSGKFI DLAIYNLSIV
61: TMQPITFYLA GRLAKKIDRV FILRFGVIFL AAFYLSVLLA GETAASRLVL IGAVLGVGYG
121: FYWLAFNVLT FEITEPDTRD FFNGFMGILS SSAGMIGPIV AGFVISRLEN NTGYTVIFSL
181: SLSLFALAVV MSFFLKRRES KGRFMLSKVF GERHSNMNWR RITNAHFFQG LREGIFVFLI
241: SVFVFIETNS ELALGTFGLV NSAVSFFAYY FASRLIKKKA RKKSILLGGL ILYGALFLIL
301: FHMSFSTLLT YGVFIAIGYP LLLVPYVSLT YDVIGRARHA RKARIEYIVL REMFLNAGRI
361: VSILCFLLIV ALLKEDVGIP LSLAILGIGH PLIYYFVKDI RFKEKEGENE TMEEDGQKRV
421: TEPTLLKGER