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Accession Number: | O75387 |
Protein Name: | Large neutral amino acids transporter small subunit 3 aka LAT3 |
Length: | 559 |
Molecular Weight: | 61477.00 |
Species: | Homo sapiens (Human) [9606] |
Number of TMSs: | 12 |
Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
Substrate | L-isoleucine, L-valine, L-leucine, L-phenylalanine |
Cross database links:
RefSeq: | NP_003618.1 |
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Entrez Gene ID: | 8501 |
Pfam: | PF07690 |
OMIM: |
603733 gene |
KEGG: | hsa:8501 hsa:8501 |
Gene Ontology
GO:0005887
C:integral to plasma membrane
GO:0015175
F:neutral amino acid transmembrane transporte...
GO:0015804
P:neutral amino acid transport
GO:0055085
P:transmembrane transport
GO:0015179
F:L-amino acid transmembrane transporter activity
GO:0015175
F:neutral amino acid transmembrane transporter activity
GO:0006811
P:ion transport
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References (10)[1] “cDNA sequencing and analysis of POV1 (PB39): a novel gene up-regulated in prostate cancer.” Cole K.A.et.al. 9722952 [2] “Identification of a novel system L amino acid transporter structurally distinct from heterodimeric amino acid transporters.” Babu E.et.al. 12930836 [3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [4] “Identification of a novel transcript up-regulated in a clinically aggressive prostate carcinoma.” Chuaqui R.F.et.al. 9255310 [5] “New insights into testicular germ cell tumorigenesis from gene expression profiling.” Skotheim R.I.et.al. 11956097 [6] “cDNA sequencing and analysis of POV1 (PB39): a novel gene up-regulated in prostate cancer.” Cole K.A.et.al. 9722952 [7] “Identification of a novel system L amino acid transporter structurally distinct from heterodimeric amino acid transporters.” Babu E.et.al. 12930836 [8] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 |
External Searches:
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Analyze:
Predict TMSs (Predict number of transmembrane segments) | ||||
FASTA formatted sequence |
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1: MAPTLQQAYR RRWWMACTAV LENLFFSAVL LGWGSLLIIL KNEGFYSSTC PAESSTNTTQ 61: DEQRRWPGCD QQDEMLNLGF TIGSFVLSAT TLPLGILMDR FGPRPVRLVG SACFTASCTL 121: MALASRDVEA LSPLIFLALS LNGFGGICLT FTSLTLPNMF GNLRSTLMAL MIGSYASSAI 181: TFPGIKLIYD AGVAFVVIMF TWSGLACLIF LNCTLNWPIE AFPAPEEVNY TKKIKLSGLA 241: LDHKVTGDLF YTHVTTMGQR LSQKAPSLED GSDAFMSPQD VRGTSENLPE RSVPLRKSLC 301: SPTFLWSLLT MGMTQLRIIF YMAAVNKMLE YLVTGGQEHE TNEQQQKVAE TVGFYSSVFG 361: AMQLLCLLTC PLIGYIMDWR IKDCVDAPTQ GTVLGDARDG VATKSIRPRY CKIQKLTNAI 421: SAFTLTNLLL VGFGITCLIN NLHLQFVTFV LHTIVRGFFH SACGSLYAAV FPSNHFGTLT 481: GLQSLISAVF ALLQQPLFMA MVGPLKGEPF WVNLGLLLFS LLGFLLPSYL FYYRARLQQE 541: YAANGMGPLK VLSGSEVTA