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2.A.1.48.1 The vacuolar basic amino acid (histidine, lysine and arginine) transporter, Vba1 (catalyzes uptake into the vacuoles (equivalent to efflux from the cytoplasm)) (most similar to family 2.A.1.3; DHA2; 13-14 putative TMSs) (Shimazu et al., 2005)
Accession Number:	Q04301
Protein Name:	Vba1 aka Permease of basic amino acids in the vacuolar membrane
Length:	562
Molecular Weight:	62640.00
Species:	Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:	14
Location¹ / Topology² / Orientation³:	Vacuole membrane¹ / Multi-pass membrane protein²
Substrate	lysine, arginine, histidine

DIP:	DIP-888N
RefSeq:	NP_013806.1
Entrez Gene ID:	855113
Pfam:	PF07690
KEGG:	sce:YMR088C
Gene Ontology GO:0000329 C:fungal-type vacuole membrane GO:0016021 C:integral to membrane GO:0015174 F:basic amino acid transmembrane transporter ... GO:0015802 P:basic amino acid transport GO:0055085 P:transmembrane transport
References (3) [1] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.” Bowman S.et.al. 9169872 [2] “A family of basic amino acid transporters of the vacuolar membrane from Saccharomyces cerevisiae.” Shimazu M.et.al. 15572352 [3] “A global topology map of the Saccharomyces cerevisiae membrane proteome.” Kim H.et.al. 16847258

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CDD Search (Conserved Domain Database)

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FASTA formatted sequence

1:	MQTLDETSNL LPPPEEAEAP PLEQKFHEYN LALPKFPILF SLWLGSFLSS LDSTIVANIM 
61:	NRVAEEFSES SKKQWIATSF LLTNTAFQPL YGKLSDITGR KSALLTAQFF FGLGCLLTCF 
121:	ARNVTEFSIA RAICGIGAGG LNAISSIAVS DICTARERGV YQGYANIVFG FGQLLGAPLG 
181:	GVFIETIGWR ALFGIQVPVI MLCSVLAIKN INIKLFHVPP MKERYTLKNL SRIDIFGSLS 
241:	LVATISGVLF LCSSQLNKLY LALFTIGSFI VFILVERYYA TEKILPFELL TRSFCLSSAV 
301:	TVISSFVVFG EIFRSPIYLQ LLQNISVTKT GLFLIFPSIS VAVGSLVTGW VLRNTKINLA 
361:	HCAYQIIFGG MIMQLLGLGL GYFLLSHLNP DYTIYDMLES ITFRSNSIWW KLIYVFASVL 
421:	VSFGYACLLV ATLVSIVFTV EKSQQGTMTG VFYLWRSIGN VLGASLTLVS YENSLSSMLW 
481:	NYMFKTKRDD EYHFTKKQYY SLINDSSYLR GPNFPTDIFV RILDVYKKAF LISYIPNIAL 
541:	AAVGIVLSLY LVKHTYKRSS SS

2.A.1.48.1
The vacuolar basic amino acid (histidine, lysine and arginine) transporter, Vba1 (catalyzes uptake into the vacuoles (equivalent to efflux from the cytoplasm)) (most similar to family 2.A.1.3; DHA2; 13-14 putative TMSs) (Shimazu et al., 2005)

Cross database links:

Gene Ontology

References (3)

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2.A.1.48.1The vacuolar basic amino acid (histidine, lysine and arginine) transporter, Vba1 (catalyzes uptake into the vacuoles (equivalent to efflux from the cytoplasm)) (most similar to family 2.A.1.3; DHA2; 13-14 putative TMSs) (Shimazu et al., 2005)

Cross database links:

Gene Ontology

References (3)

External Searches:

Analyze:

2.A.1.48.1
The vacuolar basic amino acid (histidine, lysine and arginine) transporter, Vba1 (catalyzes uptake into the vacuoles (equivalent to efflux from the cytoplasm)) (most similar to family 2.A.1.3; DHA2; 13-14 putative TMSs) (Shimazu et al., 2005)