2.A.1.49.10 MFS multidrug exporter of 429 aas and 12 TMSs. Exports capreomycin and ethidium bromide, and deletion mutants grow faster than wild type cells (Zhang et al. 2015).
|
Accession Number: | A0QYL8 |
Protein Name: | Major facilitator superfamily protein MFS_1 |
Length: | 429 |
Molecular Weight: | 44969.00 |
Species: | Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) [246196] |
Number of TMSs: | 12 |
Substrate |
ethidium bromide, capreomycin |
---|
1: MSAPQAAIDT DHADRHGPRR AWAAVGVLAL VGTLNYVDRF LPSVLAEPIK HDLELSDTAI
61: GVINGFGFLI VYAVMGIAVA RVADRGAFGA VVAGCLTLWG TMTMLGGAVQ SGFQLALTRV
121: GVAIGEAGST PAAHAYVARN FVPQRRSAPL AVITIAIPLA STASLLGGGL LAQSLGWRTA
181: FVIMGAVSVV LAPLVLLVVG VRQSLPAAPA VVDKTAGGWW NLLRKPSFLI VVAGTAFISA
241: AGYSLTTFSP AFLMRTRGMS LGEVGVEYGL ATGAIGVLGL LIVGRLADRL AERDPRWLLW
301: IVVTLTLVLL PASVLAFVVE DRMLCVLFLA LSYAIGTSYL APSIAAIQRL VLPEQRATAS
361: AMFLFFNAVF GSVGPFVVGM LSDSLTDDLG AQALGRALLL LVAAMQLVGA ICYWLASARY
421: RRDIIEEAR