2.A.1.5.4 Melibiose:H+ symporter, MelY (Shinnick et al., 2003). Transports melibiose and lactose, but not TMG, which does however bind to the transporter (Tavoulari and Frillingos, 2008)
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Accession Number: | P96517 |
Protein Name: | MelY |
Length: | 425 |
Molecular Weight: | 46701.00 |
Species: | Enterobacter cloacae [550] |
Number of TMSs: | 12 |
Location1 / Topology2 / Orientation3: |
Cell inner membrane1 / Multi-pass membrane protein2 |
Substrate |
hydron, melibiose, alpha-lactose |
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[1] “A melibiose transporter and an operon containing its gene in Enterobacter cloacae.” Okazaki N. et.al. 9209070
[2] “Sequence of a melibiose transporter gene of Enterobacter cloacae.” Okazaki N. et.al. 9375783
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1: MNTTTCTHKD NPNFWIFGLF FFLYFFIMAT CFPFLPIWLS DIIGLNKTHT GIVFSCISLS
61: AIAFQPVLGV ISDKLGLKKH LLWIISVLLF LFAPFFLYVF APLLKTNIWL GALSGGLYIG
121: FVFSAGSGAI EAYIERVSRN SAFEYGKARM FGCLGWGLCA STGGILFGID PSYVFWMGSA
181: AALLLMLLLV VAKPKPNQTA QVMNALGANQ PQITAKKVFN LFRQRRMWMF ILYVIGVACV
241: YDVFDQQFAT FFKTFFATPQ EGTRAFGFAT TAGEICNAII MFCSPWIINR IGAKNTLLIA
301: GLIMATRIIG SSFATTAVEV IALKMLHALE VPFLLVGAFK YITGVFDTRL SATIYLIGFQ
361: FAKQSAAIFL SAFAGNMYDR IGFQETYLML GCFVLAITVV SAFTLSSRQE IAAAAGAAAL
421: TSQSR