2.A.1.57.3
Iron-yersiniabactin (Ybt) transporter of 467 aas and 12 TMSs, YbtX (Bobrov et al. 2014). Yersiniabactin can also bind zinc ions with high affinity and feed the Zn2+ into this MFS transporter, YbtX (Bobrov et al. 2014). In fact, the siderophore, Ybt, is required for growth under Zn2+-deficient conditions in a strain lacking ZnuABC (see 3.A.1.15.5 for the E. coli ortholog). This MFS porter is similar to the Irp8 piscibactin secretion porter of Vibrio anguillarum (Lages et al. 2022).
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| Accession Number: | B7L8Z4 |
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| Protein Name: | Putative permease of yersiniabactin-iron transporter YbtX |
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| Length: | 467 |
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| Molecular Weight: | 49519.00 |
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| Species: | Escherichia coli (strain 55989 / EAEC) [585055] |
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| Number of TMSs: | 12 |
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| Substrate |
zinc(2+), iron atom |
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1: MSRVLMRNCS HIMDVIRRCG RRKWPRACGA TTGFPRLESG CMSDVQSNVK PLTLTTGRVI
61: FAIAGVYVTQ SLVSALSMQS LPALVRAAGG SLALAGATTL FMLPWALKFI WASWIERWRL
121: PPGSQERRSR MLILRGQVAL AAILTIVAAI GWFGREGGFP DTQIVALFVL FMVAGTVAST
181: IDIASDGFCV DQLTRTGYGW GNSVQVGGSY LGMMCGGGVF LMLSAASGWP VAMLMMAVLI
241: MALSLPLWRI TEPTRTATIP HVPALGYALR RKQARLGLLL VLMLNSGMRF VLPLLAPLLL
301: DHGLSMSALG ALFSGGNIAA GIAGTLAGGL LMKYTSPGRA LLTAYGVQGI ALLAVVMTLM
361: MAPGHLLLQI LQCLVLVQSI SLACALVCLY ATLMSLSSPL QAGVDFTLFQ CTDAAIAILA
421: GVIGGVVAQH FGYAACFLFA GAFTLLAAWV AYIRLHSARE LMTSAID