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2.A.1.65.1 The putative MFS carrier, Sugar Baby (Sug, isoform D); has a hydrophilic domain between TMSs 3 and 4. Overexpression causes an increased lifespan by 17%. It has 12 TMSs in a 3 + 3 + 6 TMS arrangement.
Accession Number:	Q7KUF9
Protein Name:	Sug, isoform D
Length:	625
Molecular Weight:	69510.00
Species:	Drosophila melanogaster (Fruit fly) [7227]
Number of TMSs:	12
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate

RefSeq:	NP_996057.2
Entrez Gene ID:	39314
Pfam:	PF07690
Gene Ontology GO:0008340 P:determination of adult lifespan GO:0055085 P:transmembrane transport
References (2) [1] “Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.” Misra S.et.al. 12537572 [2] “The genome sequence of Drosophila melanogaster.” Adams M.D.et.al. 10731132

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MKATIDKELL PMKAHYFLFN AGTAPVVPFM PTLAGQLGYS PAVVGTMYTI LPIIGMLAKP 
61:	LFGYIADRYH RHRPLFLGGQ VLTGIAFFLI MFVPGMEKPL PKVEFHCHQG VSDIPRFCSE 
121:	YGECVERNLE RYYGNRTLEC ELNCEAQPFM WDIVCEDWLK NNTENCAANR TNTQMEFGAS 
181:	ITMQKIENDG SCMFFMIPHD QGQIAGQNVT LYCPKEKEYF KSNCTMDCRE DYLKEQLAES 
241:	AVINTSSAVT MPQFWLFFGL LIFSWIGMAV VVSIGDAICF GILGDRHHLY GKQRLCGSLG 
301:	WGVFALLAGL LVDHMSLGEV NKNYTAVFWM ALLIMGFDVF ASSKLRVSIS ETENPFLKLK 
361:	FPYSKLQHTP THLSSNILKD VGQMFLSVRC VIFFLWCVAI GLGTALIWNF LFIYLEELDK 
421:	AFEGCDSSIK TLEGLVMGIQ CFGGELPFFF LSGWILKKIG HVNAMSVVLF GFGVRFILYS 
481:	MLQNPWYILP IELMNGVTFG LFYATMASYA SIVAPPGTDA TMQSLVGAIF EGVGVSMGSL 
541:	IAGQLFESVT ARTTFEIFGI GAFIVFVIHV CIQLYLQRNS NIDENGKGTV ASASATASPS 
601:	APLETDIPKN TDHKDGDGFR EVDLS

2.A.1.65.1
The putative MFS carrier, Sugar Baby (Sug, isoform D); has a hydrophilic domain between TMSs 3 and 4. Overexpression causes an increased lifespan by 17%. It has 12 TMSs in a 3 + 3 + 6 TMS arrangement.

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

2.A.1.65.1The putative MFS carrier, Sugar Baby (Sug, isoform D); has a hydrophilic domain between TMSs 3 and 4. Overexpression causes an increased lifespan by 17%. It has 12 TMSs in a 3 + 3 + 6 TMS arrangement.

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

2.A.1.65.1
The putative MFS carrier, Sugar Baby (Sug, isoform D); has a hydrophilic domain between TMSs 3 and 4. Overexpression causes an increased lifespan by 17%. It has 12 TMSs in a 3 + 3 + 6 TMS arrangement.