2.A.1.65.13
MFSD6 of 791 aas and 12 TMSs in a 3 + 3 + 6 TMS arrangement. Mutations in the mfsd-6 gene influence the regulation of neural circuit activity (McCulloch et al. 2017). MfsD6 may transport sugars.
|
| Accession Number: | Q6ZSS7 |
|---|
| Protein Name: | Major facilitator superfamily domain-containing protein 6 |
|---|
| Length: | 791 |
|---|
| Molecular Weight: | 88088.00 |
|---|
| Species: | Homo sapiens (Human) [9606] |
|---|
| Number of TMSs: | 12 |
|---|
| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
|---|
| Substrate |
|
|---|
1: MADDKVAILT DDEEEQKRKY VLADPFNGIS REPEPPSNET PSSTETSAIP EEEIDWIEKH
61: CVKINNDLLI SKVFYFFFYS AYGSLYPLLP VYYKQLGMSP SQSGLLVGIR YFIEFCSAPF
121: WGVVADRFKK GKIVLLFSLL CWVLFNLGIG FVKPATLRCV PKIRPTTHPT NASHQLTILP
181: TNSSFTSFLT ISPKMREKRN LLETRLNVSD TVTLPTAPNM NSEPTLQPQT GEITNRMMDL
241: TLNSSTATPV SPGSVTKETT TVIVTTTKSL PSDQVMLVYD QQEVEAIFLV ILVVVIIGEF
301: FSASSVTIVD TVTLQYLGKH RDRYGLQRMW GSLGWGLAML SVGIGIDYTH IEVLIDGKGC
361: KPPEYRNYQI VFIVFGVLMT MALIVATQFR FRYNHFKNDD SKGKEVEIPQ VERNNSTESS
421: EETPTTTSHS QAFNFWDLIK LLCSVQYGSV LFVAWFMGFG YGFVFTFLYW HLEDLNGTTT
481: LFGVCSVLSH VSELTAYFFS HKLIELIGHI RVLYIGLACN TARYIYISYL ENAWTVLPME
541: VLQGVTHAAI WAACISYLSA AVPPELRTSA QGILQGLHLG LGRGCGAMIG GVLVNYFGAA
601: ATFRGIGMAC LVILLLFALI QWLAVPDEEE DKTMLAERIP VPSSPVPIAT IDLVQQQTED
661: VMPRIEPRLP PKKTKHQEEQ EDVNKPAWGV SSSPWVTFVY ALYQIKEMMQ LTRDNRASEI
721: QPLQGTNENR ENSPAGRAQP VPCETHSDPS RNQPSPDAAA SQTQTSPAHP SVDPCTEESE
781: EQQAQLAAGG H