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2.A.1.8.5 Nitrate/nitrite transporter/antiporter, CrnA/NrtA (Unkles et al., 1991; Beckham et al. 2010). The nitrate signature sequences (NS1 and NS2) in TMSs 5 and 11 and arg residues in TMSs 2 and 8 may influence substrate binding (Unkles et al., 2012).
Accession Number:	P22152
Protein Name:	CrnA
Length:	507
Molecular Weight:	54925.00
Species:	Emericella nidulans (Aspergillus nidulans) [162425]
Number of TMSs:	12
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	nitrite, nitrate

RefSeq:	XP_658612.1
Entrez Gene ID:	2876788
Pfam:	PF07690
KEGG:	ani:AN1008.2
Gene Ontology GO:0016021 C:integral to membrane GO:0015103 F:inorganic anion transmembrane transporter a... GO:0015698 P:inorganic anion transport GO:0042128 P:nitrate assimilation GO:0055085 P:transmembrane transport
References (2) [1] “crnA encodes a nitrate transporter in Aspergillus nidulans.” Unkles S.E.et.al. 1986367 [2] “Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae.” Galagan J.E.et.al. 16372000

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MDFAKLLVAS PEVNPNNRKA LTIPVLNPFN TYGRVFFFSW FGFMLAFLSW YAFPPLLTVT 
61:	IRDDLDMSQT QIANSNIIAL LATLLVRLIC GPLCDRFGPR LVFIGLLLVG SIPTAMAGLV 
121:	TSPQGLIALR FFIGILGGTF VPCQVWCTGF FDKSIVGTAN SLAAGLGNAG GGITYFVMPA 
181:	IFDSLIRDQG LPAHKAWRVA YIVPFILIVA AALGMLFTCD DTPTGKWSER HIWMKEDTQT 
241:	ASKGNIVDLS SGAQSSRPSG PPSIIAYAIP DVEKKGTETP LEPQSQAIGQ FDAFRANAVA 
301:	SPSRKEAFNV IFSLATMAVA VPYACSFGSE LAINSILGDY YDKNFPYMGQ TQTGKWAAMF 
361:	GFLNIVCRPA GGFLADFLYR KTNTPWAKKL LLSFLGVVMG AFMIAMGFSD PKSEATMFGL 
421:	TAGLAFFLES CNGAIFSLVP HVHPYANGIV SGMVGGFGNL GGIIFAIIFR YSHHDYARGI 
481:	WILGVISMAV FISVSWVRPV PKSQMRE

2.A.1.8.5
Nitrate/nitrite transporter/antiporter, CrnA/NrtA (Unkles et al., 1991; Beckham et al. 2010). The nitrate signature sequences (NS1 and NS2) in TMSs 5 and 11 and arg residues in TMSs 2 and 8 may influence substrate binding (Unkles et al., 2012).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

2.A.1.8.5Nitrate/nitrite transporter/antiporter, CrnA/NrtA (Unkles et al., 1991; Beckham et al. 2010). The nitrate signature sequences (NS1 and NS2) in TMSs 5 and 11 and arg residues in TMSs 2 and 8 may influence substrate binding (Unkles et al., 2012).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

2.A.1.8.5
Nitrate/nitrite transporter/antiporter, CrnA/NrtA (Unkles et al., 1991; Beckham et al. 2010). The nitrate signature sequences (NS1 and NS2) in TMSs 5 and 11 and arg residues in TMSs 2 and 8 may influence substrate binding (Unkles et al., 2012).