2.A.1.86.1
MFS uptake permease. The gene is adjacent to a putative SAM-dependent methyl transferase, one homologue of which is a puromycin methyl transferase. Perhaps the transport substrate is a drug that is modified by methylation for detoxification purposes. This family is most closely, but distantly related to the AAHS family (2.A.1.15).
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| Accession Number: | Q1DA07 |
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| Protein Name: | Putative membrane protein |
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| Length: | 731 |
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| Molecular Weight: | 77769.00 |
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| Species: | Myxococcus xanthus (strain DK 1622) [246197] |
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| Number of TMSs: | 13 |
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| Substrate |
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1: MLRAALLVLV TSCATLVLEL AAARLLAPFI GASLHTWTSI IGVVLAGISL GSYAGGRLSE
61: RGASFRWLAG LTALGAVLAL LPLGWVAVLG DGAALRPIPV LPRTFLLTFL GFFPVSFVLA
121: MVTPLALRLL LPDLGRAGRI VGLLYALGTL GSLAGNFLTG FVLVAWFPVP TIVLTVSGAL
181: MLCALLALPK ASVSAPPVEP AAPATAGAVT AADAAPSSTG VDLRTRPVLA CFLVASASFC
241: TLAIELAASR ILAPTVGVSL LSWTGIIGVV LTGMALGNFL GGHLADRWPR QEVLAGSMLL
301: AAASCLLIPP IHQWLVLKGY FDGLGLQARI VGYTAAVFLL PVTALGTLSP QVLRLALADV
361: ERAGRTVGRL YAWSTAGALL GSFLTGWWLI AKVGVYPLVM GASLGLVALA AFVGQVWRRP
421: LFVGATAGTL ALAGMFGALG LFASPCTEET DYFCIKVNQV EHDGRRLLAM QLDHLTHTMV
481: DLEDPSYLGY PHGYIHSEVV RHVAARTAEP RVLVIGGGGY VVPRWVETYV PQVRMEVVEI
541: DPAVTRIALE RFGVKPDTRI ASFSLDGRQY LQEMAERGAY DLIVQDAVND LSVPYHLMTR
601: EYDMLVRSLL KPDGLYLLTV IDEIPRGSFL RSALRTMQEV FPHVELLHDA RSGSKGQGVY
661: IVAGSARPME LERLPELLRG VGIEQPRTGR VPRAEIDAYL AAGPALLLTD DFAPVDNLLA
721: ELFLLREQVA P