| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
2.A.110.1.1 | The endosomal/lysosomal heme transporter, HRG-1 (SLC48.1) (Yuan et al., 2012) | Eukaryota |
Metazoa, Chordata | SLC48A1 of Homo sapiens |
|
2.A.110.1.2 | The worm heme transporter, HRG-1 (Yuan et al., 2012). | Eukaryota |
Metazoa, Nematoda | HRG1 of Caenorhabditis elegans (Q21642) |
|
2.A.110.1.3 | HRG-4 heme transporter (Rajagopal et al. 2008). | Eukaryota |
Metazoa, Nematoda | HRG-4 of Caenorhabditis elegans (Q20106) |
|
2.A.110.1.4 | Putative heme transporter (151aas; 4 TMSs) | Eukaryota |
Metazoa, Chordata | Heme transporter of Branchiostoma floridae (C3Y137) |
|
2.A.110.1.5 | Eukaryota |
Metazoa, Nematoda | Hrg-6 of Caenorhabditis elegans | |
|
2.A.110.1.6 | HRG homologue | Eukaryota |
Discosea | HRG homologue of Acanthamoeba castellanii |
|
2.A.110.2.1 | The LHR1 heme uptake transporter (Huynh et al. 2012). In Leishmania amazonensis, LHR1 is essential for virulence (Miguel et al. 2013). Transport depends on tyrosyl residues in the first three TMSs of the protein (Renberg et al. 2015). | Eukaryota |
Euglenozoa | LHR1 of Leishmania donovani (E9BH93) |
|
2.A.110.2.2 | Heme uptake transporter, LHR1 (171aas; 4 putative TMSs) (Huynh et al. 2012). Tyrosyl residues essential for activity are also essential for virulence (Renberg et al. 2015). | Eukaryota |
Euglenozoa | LHR1 of Trypanosoma cruzi (Q4DHZ7) |