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TCID	Name	Domain	Kingdom/Phylum	Protein(s)
2.A.113.1.1	Ni²⁺/Co²⁺ exporter, RcnA/RcnB (Rodrigue et al., 2005; Iwig et al., 2006). RcnB, a small 1 or 2 TMS protein of the DUF3315 or PF11776 family, regulates the activity of RcnA.	Bacteria	Pseudomonadota	RcnAB of E. coli RcnA (P76425) RcnB (P64534)
2.A.113.1.2	Ni²⁺ resistance protein, like NcrC	Bacteria	Pseudomonadota	NcrC homologue of Enterobacter cloaecae (D5CKG5)
2.A.113.1.3	RcnA homologue	Bacteria	Pseudomonadota	RcnA homologue of Ralstonia solanacearum (CAD17703)
2.A.113.1.4	Urease accessory protein, UreH	Archaea	Euryarchaeota	UreH of Methanocaldococcus jannaschii (Q58492)
2.A.113.1.5	NiCoT homologue of 6 TMSs with two putative 3 TMS repeats corresponding to TMSs 2-4 and 6-8 in the 8 TMS homologues (B Tsu and DC Yee, unpublished)	Bacteria	Acidobacteriota	NiCoT homologue of Solibacter usitatus
2.A.113.1.6	NicO homologue of 6 TMSs with TMSs 1-3 corresponding to TMSs 2-4 in the 8 TMS homologues, and TMSs 6-8 corresponding to TMSs 6-8 in the 8 TMS homologues (B Tsu and DC Yee, unpublished).	Bacteria	Planctomycetota	NicO homologue of Rhodopirellula baltica
2.A.113.1.7	Putative high affinity Ni²⁺ transporter of 320 aas and 7 TMSs in a 1 3 3 arrangement.	Bacteria	Pseudomonadota	Nickel transporter of Starkeya novella
2.A.113.1.8	Uncharacterized protein of 244 aas and 6 TMSs.	Bacteria	Fusobacteriota	UP of Fusobacterium nucleatum
2.A.113.1.9	Uncharacterized protein of 232 aas and 6 TMSs	Bacteria	Pseudomonadota	UP of Oligotropha carboxidovorans
2.A.113.1.10	Nickel/Cobalt uptake porter, NcrC of 231 aas (Marrero et al. 2007). This sequence is proably a partial sequence lacking the C-terminal 3-TMS domain as exists in it's closest homologues such as 2.A.113.1.2.	Bacteria	Pseudomonadota	NcrC of Serratia marcescens
2.A.113.1.11	NicO homologue of 236 aas and 6 TMSs.	Bacteria	Bacillota	NicO homologue of Geobacillus thermoleovorans
2.A.113.1.12	NicO homologue of 218 aas and 6 TMSs.	Archaea	Euryarchaeota	NicO of Haloferax mediterrainei
2.A.113.1.13	NicO homologue of 284 aas and 6 TMSs.	Bacteria	Thermomicrobiota	NicO of Sphaerobacter thermophilus
2.A.113.1.14	Putative high affinity nickel transporter	Bacteria	Spirochaetota	Putative Ni²⁺transporter of Treponema denticola
2.A.113.2.1	High affinity Nickel transporter of 556 aas and 8 or 9 TMSs in a 1 + 4 +3 or 4 TMS arrangement. TMS 1 is N-terminal. distant from the others. Then there are 4 TMSs followed by a hydrophilic regiion with one peak of very weak hydrophobicity. This is followed by 3 clear TMSs.	Bacteria	Actinomycetota	NicO family member of Streptomyces griseus
2.A.113.2.2	Putative Nickel transporter of 597 aas and 7 TMSs in a 1 (N-terminal) + 3 + 3 arrangement.	Bacteria	Actinomycetota	NicO family member in Streptomyces ipomoeae
2.A.113.2.3	Uncharacterized protein of 488 aas and 7 TMSs in a clear 1 + 3 + 3 arrangement.	Bacteria	Cyanobacteriota	UP of Nostoc punctiforme