2.A.122.1.1 LrgB (YohK) protein (putative murein hydrolase export regulator; LrgA-associated protein) (7 probable TMSs based on topological analyses. This protein and 2.A.122.1.2 with 8 TMSs appear to derive from a 4 TMS precursor that duplicated to give 8, and LrgB may have lost TMS 1. It does not appear to be a member of the TOG superfamily.). LrgB decreases antibiotic sensitivity (Yang et al., 2005). More recently, it was suggested to be a 3-hydroxypropionate exporter, functioning together with YhoJ ( 1.E.14.1.4) of 132 aas and 4 TMSs (Nguyen-Vo et al. 2020).
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Accession Number: | C6EAH0 |
Protein Name: | LrgB family protein |
Length: | 231 |
Molecular Weight: | 24470.00 |
Species: | Escherichia coli (strain B / BL21-DE3) [469008] |
Number of TMSs: | 5 |
Substrate |
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Pfam: |
PF04172
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[1] “Genome sequences of Escherichia coli B strains REL606 and BL21(DE3).” Jeong H. et.al. 19786035
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1: MMANIWWSLP LTLIVFFAAR KLAARYKFPL LNPLLVAMVV IIPFLMLTGI SYDSYFKGSE
61: VLNDLLQPAV VALAYPLYEQ LHQIRARWKS IITICFIGSV VAMVTGTSVA LLMGASPEIA
121: ASILPKSVTT PIAMAVGGSI GGIPAISAVC VIFVGILGAV FGHTLLNAMR IRTKAARGLA
181: MGTASHALGT ARCAELDYQE GAFSSLALVL CGIITSLIAP FLFPIILAVM G