2.A.128.1.20 Teicoplanin resistance protein, VanZ1 of 169 aas and 5 (or 6) putative TMSs in a 1 + 4 arrangement (or in a 6 TMS arrangement). Its synthesis is induced by the antiicrobial peptide, LL-37 (1.C.33.1.10), but not by many other antimicrobials tested (Woods et al. 2018).
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Accession Number: | Q18BA1 |
Protein Name: | Teicoplanin resistance protein |
Length: | 169 |
Molecular Weight: | 18966.00 |
Species: | Peptoclostridium difficile (strain 630) [272563] |
Number of TMSs: | 5 |
Substrate |
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1: MKSRKHNITK GLFIVYIIIL TWIILFKLQF DISSLETMNL RSINLVPFAG SLIINNRVDI
61: SEIILNVAIF VPFGIYVCML KEEWSFIKKV IPIFITSLAF ETLQYIFALG ASDITDLIGN
121: TLGGIIGIAV FMLLSKIFKN NTIKIINVLA LIVTIIVVLF LGLVIFANL