TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
2.A.128.1.1









The 4 TMS VanZ MDR export system confers resistance to teicoplanin and dalbavancin in Streptococcus agalactiae (Lai et al. 2017).

Bacteria
Firmicutes
VanZ of Streptococcus agalactiae
2.A.128.1.2









VanZ homologue of 210 aas and 5 TMSs.

Bacteria
Firmicutes
VanZ of Bacillus cereus
2.A.128.1.3









VanZ homologue of 181 aas and 5 TMSs

Bacteria
Firmicutes
VanZ of Listeria grandensis
2.A.128.1.4









VanZ homologue of 143 aas and 4 TMSs

Bacteria
Firmicutes
VanZ of Ruminococcus flavefaciens
2.A.128.1.5









VanZ/RDD domain protein of 386 aas and 9 TMSs

Bacteria
Firmicutes
VanZ/RDD protein of Erysipelothrix rhusiopathiae
2.A.128.1.6









VanZ homologue of 243 aas and 5 TMSs.

Bacteria
Actinobacteria
VanZ of Amycolatopsis orientalis
2.A.128.1.7









VanZ homologue of 162 aas and 4 TMSs.

Bacteria
Actinobacteria
VanZ of Streptomyces afghaniensis
2.A.128.1.8









VanZ homologue of 202 aas and 5 TMSs

Bacteria
Actinobacteria
VanZ of Cellulosimicrobium cellulans
2.A.128.1.9









VanZ homologue of 436 aas and 7 TM

Bacteria
Tenericutes
VanZ of Mycoplasma sp. CAG:472
2.A.128.1.10









VanZ homologue of 224 aas and 6 TMSs

Bacteria
Bacteroidetes
VanZ homologue of Flavisolibacter ginsengisoli
2.A.128.1.11









VanZ family proteinof 122 aas and 4 TM

Bacteria
Bacteroidetes
VanZ of Roseivirga seohaensis
2.A.128.1.12









Teicoplanin resistance protein VanZ of 120 aas and 4 TMSs.

Bacteria
Proteobacteria
VanZ of Campylobacter concisus
2.A.128.1.13









VanZ family proteinof 204 aas and 5 TMSs

Bacteria
Bacteroidetes
VanZ of Parapedobacter indicus
2.A.128.1.14









VanZ family proteinof 125 aas and 4 TM

Bacteria
Cyanobacteria
VanZ of Nostoc carneum
2.A.128.1.15









Uncharacterized protein of 247 aas and 8 TMSs, where the first 4 TMSs are homologous to VanZ proteins

Bacteria
Planctomycetes
UP of Phycisphaerae bacterium
2.A.128.1.16









VanZ family proteinof 119 aas and 4 TMSs.

Bacteria
Chlorobi
VanZ of Pelodictyon phaeoclathratiforme
2.A.128.1.17









VanZ like family proteinof 118 aas and 4 TM

Bacteria
Bacteroidetes
VanZ of Flavobacterium terrigena
2.A.128.1.18









VanZ like family proteinof 270 aas and 4 central TM

Eukaryota
Fungi
VanZ of Colletotrichum nymphaeae
2.A.128.1.19









VanZ family protein of 202 aas and 5 TMSs in a 1 + 2 + 2 arrangement.

Bacteria
Firmicutes
VanZ of Enterococcus asini
2.A.128.1.20









Teicoplanin resistance protein, VanZ1 of 169 aas and 5 (or 6) putative TMSs in a 1 + 4 arrangement (or in a 6 TMS arrangement). Its synthesis is induced by the antiicrobial peptide, LL-37 (1.C.33.1.10), but not by many other antimicrobials tested (Woods et al. 2018).

Bacteria
Firmicutes
VanZ1 of Peptoclostridium difficile (Clostridium difficile)
2.A.128.2.1









VanZ family protein of 163 aas and 4 TM

Bacteria
Planctomycetes
VanZ of Blastopirellula cremea
2.A.128.2.2









Teicoplanin resistance protein, VanZ of 164 aas and 3 or 4 TMSs.

Bacteria
Firmicutes
VanZ of Clostridium acetobutylicum
2.A.128.2.3









UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase of 743 aas and an N-terminal hydrophobic domain with 4 TMSs that are homologous to VanZ family members.

Bacteria
Firmicutes
N-terminal VanZ domain protein of Eubacterium sp. An3
2.A.128.2.4









VanZ family proteinof 135 aas and 4 TMSs.

Bacteria
Firmicutes
VanZ of Cohnella thermotolerans
2.A.128.2.5









Uncharacterized proteinof 203 aas and 6 TMSs.

Archaea
Euryarchaeota
UP of Methanolobus vulcani
2.A.128.2.6









VanZ family protein of 129 aas andd 4 TMSs

Bacteria
Actinobacteria
VanZ of Asaccharobacter celatus
2.A.128.2.7









VanZ like family proteinof144 aas and 4 TMSs.

Archaea
Candidatus Lokiarchaeota
VanZ of Lokiarchaeum sp.
2.A.128.2.8









VanZ family protein of 158 aas and 4 TMSs.

Bacteria
PVC group
VanZ of Verrucomicrobia bacterium (marine metagenome)