2.A.13.1.6
Dicarboxylate transporter, DcuB of 474 aas and 11 TMSs. Takes up aspartate and secretes succinate. Subject to regulation in response to oxygen and nitrate, mediated by the sensor kinase/response regulator pair, RacR/RacS (Wösten et al. 2017).
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| Accession Number: | Q0PAK3 |
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| Protein Name: | Anaerobic C4-dicarboxylate transporter |
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| Length: | 474 |
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| Molecular Weight: | 51041.00 |
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| Species: | Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) [192222] |
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| Number of TMSs: | 11 |
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| Location1 / Topology2 / Orientation3: |
Cell inner membrane1 / Multi-pass membrane protein2 |
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| Substrate |
aspartate(2-), succinate(2-) |
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1: MDFLTSLSEA GQFAIQIIIV LICLFYGAKK GGIALGLLGG IGILMLVFAF HIKPGKPAID
61: VMLTILAVVV ASATLQASGG LDVMLQIAER ILRRNPKFLT ILAPFVTCFL TILCGTGHVV
121: YTIMPIIYDI AIKNGIRPER PMVAASISSQ MGIIASPVSV AVVSLTALLL NANHKLAGFD
181: GYINLLQITI PSTLFGVLCI GIFSWFRGKD LDKDEVFQEK LKDPEFKKYV YGDSKTLLGV
241: KLPKSNWVAM WIFLGAIALV ALLGVFDFLR PNWGQVVKNG IPQVDALGNP KMDVLSMVSV
301: IQMFMLLAGS LIIIFTKTDA KKIGSNEIFK SGMIALVAVF GISWMADTMF AVHTPMMKAA
361: LGDIVKEHPW TYAVMLLLIS KFVNSQAAAI SAFVPLALGI GVEPGVIVAF AAACYGYYIL
421: PTYPSDLATI QFDRSGTTHI GKFVINHSFI LPGLIGVITS CIAGYFIAMA AGYL