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2.A.23.2.10
Excitatory amino acid transporter (Sodium-dependent glutamate/aspartate transporter), Gkt-1 of 503 aas and 9 - 11 TMSs (Radice and Lustigman 1996).

Accession Number:Q10901
Protein Name:Excitatory amino acid transporter
Length:503
Molecular Weight:54676.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:9
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate sodium(1+), glutamate(2-), aspartate(2-)

Cross database links:

Entrez Gene ID: 180641   
Pfam: PF00375   
KEGG: cel:C12D12.2   

Gene Ontology

GO:0042995 C:cell projection
GO:0016021 C:integral to membrane
GO:0005313 F:L-glutamate transmembrane transporter activity
GO:0017153 F:sodium:dicarboxylate symporter activity

References (5)

[1] “Cloning and characterization of cDNAs encoding putative glutamate transporters from Caenorhabditis elegans and Onchocerca volvulus.”  Radice A.D.et.al.   8885221
[2] “Molecular cloning of a cDNA for the glutamate transporter of the nematode Caenorhabditis elegans.”  Kawano T.et.al.   8920929
[3] “Structure and activity of a new form of the glutamate transporter of the nematode Caenorhabditis elegans.”  Kawano T.et.al.   9178573
[4] “Genome sequence of the nematode C. elegans: a platform for investigating biology.”  The C. elegans sequencing consortiumet.al.   9851916
[5] “Identification of the hydrophobic glycoproteins of Caenorhabditis elegans.”  Fan X.et.al.   15888633

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MPPDTRINKE IMVSWIRKNL LLVLTVSSVV LGALCGFLLR GLQLSPQNIM YISFPGELLM 
61:	HMLKMMILPL IMSSLISGLA QLDARQSGKL GSLAVTYYMF TTAVAVVTGI FLVLVIHPGD 
121:	PTIKKEIGTG TEGKTVSTVD TLLDLLRNMF PENVVQATFQ QVQTKYIKVR PKVVKNNDSA 
181:	TLAALNNGSL DYVKASVEYT SGMNVLGVIV FCIAIGISLS QLGQEAHVMV QFFVIMDKVI 
241:	MKLVMTVMWY SPFGIFCLIM GKILEIHDLA DTARMLAMYM VTVLSGLAIH SLISLPLIFF 
301:	VTTKKNPYVF MRGLFQAWIT ALGTASSSAT LPITFNCLEE NLGVDRRVTR FVLPVGATIN 
361:	MDGTALYEAV AAIFIAQING VHLSFGQVVT VSLTATLASI GAASVPSAGL VTMLLVLTAV 
421:	GLPVKDVSLI VAVDWLLDRI RTSINVLGDA MGAGIVYHYS KADLDAHDRL AATTRSHSIA 
481:	MNDEKRQLAV YNSLPTDDEK HTH